FMOC-ARG(ME,PBF)-OH
- CAS NO.:1135616-49-7
- Empirical Formula: C35H42N4O7S
- Molecular Weight: 662.8
- MDL number: MFCD08064312
- SAFETY DATA SHEET (SDS)
What is FMOC-ARG(ME,PBF)-OH?
Description
FMOC-Arg (ME, PBF)-OH is a kind of protected form of arginine. Arginine is double-protected by butyloxycarbonyl (BOC) and 2, 2, 4, 6, 7-pentamethyldihydrobenzofuran-5-sulfonyl (PBF). It is a derivative for introducing mono-methyl-arginine during Fmoc SPPS. Coupling can be carried out using any standard activation method. PBF protecting group can be removed by TFA-mediated cleavage reaction. As a kind of protected amino acid, it is an important intermediate in various fields such as peptide synthesis, asymmetric synthesis, medicinal chemistry as well as polymer chemistry.
Chemical properties
White powder
The Uses of FMOC-ARG(ME,PBF)-OH
Fmoc-?Arg(Me,?pbf)?-?OH can be used as reactant/reagent in design, synthesis and structure-activity relationship of macrocyclic peptidomimetics that bind to WDR5 and block WDR5-MLL protein-protein interaction.
References
https://www.merckmillipore.com/CN/zh/product/Fmoc-Arg%28Me%2CPbf%29-OH,MDA_CHEM-852105?ReferrerURL=https%3A%2F%2Fguge6.firstguo.com%2F&bd=1
https://en.wikipedia.org/wiki/Peptide_synthesis
Kim, Tae-il, et al. "Arginine-conjugated polypropylenimine dendrimer as a non-toxic and efficient gene delivery carrier." Biomaterials 28.11 (2007): 2061-2067.
Properties of FMOC-ARG(ME,PBF)-OH
Density | 1.33 |
storage temp. | Store at -15°C to -25°C. |
pka | 3.80±0.21(Predicted) |
Safety information for FMOC-ARG(ME,PBF)-OH
Computed Descriptors for FMOC-ARG(ME,PBF)-OH
New Products
ALUMINIUM IODIDE 100 GM BUFFER CAPSULE PH 7.0 - 10 CAP BUFFER SOLUTION PH 9.5 (BORATE) EZEE BLUE GEL STAINER BORAX CARMINE (GRENACHERS ALCOHOLIC) POTASSIUM IODATE - IODIDE SOLN 0.1 N Dabigatran Acyl-O3-D-Glucuronide Trifluoroacetic Acid Salt Isofolic Acid Dabigatran 2-O-acylglucuronide metabolite Dabigatran Acyl-?-D- glucuronide Trifluroacetic Acid Erythromycin EP Impurity A Desloratidine Related Compound ARelated products of tetrahydrofuran
You may like
-
Fmoc-Arg(Me,pbf)-OH 98% (HPLC) CAS 1135616-49-7View Details
1135616-49-7 -
Fmoc-arg(me,pbf)-oh 95% CAS 1135616-49-7View Details
1135616-49-7 -
Fmoc-Arg(Me,Pbf)-OH CAS 1135616-49-7View Details
1135616-49-7 -
Dechloro DesloratadineView Details
-
Dehydro DesloratadineView Details
-
Edoxaban Impurity 57View Details
2089454-69-1 -
Empagliflozin Bromo ImpurityView Details
-
Ipratropium EP Impurity BView Details
58073-59-9