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HomeProduct name listFMOC-6-AMINOHEXANOIC ACID

FMOC-6-AMINOHEXANOIC ACID

Synonym(s):6-(Fmoc-amino)caproic acid;6-(Fmoc-amino)hexanoic acid

FMOC-6-AMINOHEXANOIC ACID Structural

What is FMOC-6-AMINOHEXANOIC ACID?

Description

Fmoc-6-aminohexanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Fmoc-6-aminohexanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Chemical properties

White powder

The Uses of FMOC-6-AMINOHEXANOIC ACID

Fmoc-6-aminohexanoic acid, is an amino acid derivative used in chemical synthesis and peptide chemistry.

What are the applications of Application

Fmoc-6-Ahx-OH is a specialty product for proteomics research applications

Properties of FMOC-6-AMINOHEXANOIC ACID

Melting point: 114 °C
Boiling point: 582.7±33.0 °C(Predicted)
Density  1.210±0.06 g/cm3(Predicted)
storage temp.  2-8°C
solubility  Soluble in water or 1% acetic acid
form  Powder
pka 4.75±0.10(Predicted)
color  White
Water Solubility  Soluble in 1% acetic acid, water and 1mmol in 2mL DMF clearly soluble.
BRN  5883220
CAS DataBase Reference 88574-06-5(CAS DataBase Reference)

Safety information for FMOC-6-AMINOHEXANOIC ACID

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405:Store locked up.

Computed Descriptors for FMOC-6-AMINOHEXANOIC ACID

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