FMOC-6-AMINOHEXANOIC ACID
Synonym(s):6-(Fmoc-amino)caproic acid;6-(Fmoc-amino)hexanoic acid
- CAS NO.：88574-06-5
- Empirical Formula: C21H23NO4
- Molecular Weight: 353.41
- MDL number: MFCD00077045
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02
What is FMOC-6-AMINOHEXANOIC ACID?
Description
Fmoc-6-aminohexanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Fmoc-6-aminohexanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Chemical properties
White powder
The Uses of FMOC-6-AMINOHEXANOIC ACID
Fmoc-6-aminohexanoic acid, is an amino acid derivative used in chemical synthesis and peptide chemistry.
What are the applications of Application
Fmoc-6-Ahx-OH is a specialty product for proteomics research applications
Properties of FMOC-6-AMINOHEXANOIC ACID
| Melting point: | 114 °C |
| Boiling point: | 582.7±33.0 °C(Predicted) |
| Density | 1.210±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Soluble in water or 1% acetic acid |
| form | Powder |
| pka | 4.75±0.10(Predicted) |
| color | White |
| Water Solubility | Soluble in 1% acetic acid, water and 1mmol in 2mL DMF clearly soluble. |
| BRN | 5883220 |
| CAS DataBase Reference | 88574-06-5(CAS DataBase Reference) |
Safety information for FMOC-6-AMINOHEXANOIC ACID
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for FMOC-6-AMINOHEXANOIC ACID
New Products
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