Fluo-2 AM
- CAS NO.：1070771-36-6
- Empirical Formula: C51H52N2O23
- Molecular Weight: 1060.96
- Update Date: 2023-05-21 10:59:17
What is Fluo-2 AM?
Biological Activity
Fluo-2 AM is a cell-permeable fluorescent calcium indicator.1,2 It has been used to measure the activity of the neuropeptide Y4 receptor, as well as to detect intracellular calcium in tetrandine-stimulated primary rabbit corpus cavernosum smooth muscle cells. It binds to calcium (Kd = 290 nM) and displays excitation/emission maxima of 490/515 nm, respectively. Fluo-2 AM is also available in a cell-impermeable form .
References
1.Sliwoski, G., Schubert, M., Stichel, J., et al.Discovery of small-molecule modulators of the human Y4 receptorPLoS One11(6)e0157146(2016) 2.Liu, J.-H., Chen, J., Wang, T., et al.Effects of tetrandrine on cytosolic free calcium concentration in corpus cavernosum smooth muscle cells of rabbitsAsian J. Androl.8(4)405-409(2006)
Properties of Fluo-2 AM
| storage temp. | -20°C |
| form | A solid |
Safety information for Fluo-2 AM
Computed Descriptors for Fluo-2 AM
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