Flavanomarein

CAS NO.：577-38-8
Empirical Formula: C21H22O11
Molecular Weight: 450.39
MDL number: MFCD00136058
EINECS: 209-411-1
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-04 20:04:50

What is Flavanomarein?

Chemical properties

Flavanomarein, known as isookanin-7-o-glucoside, is a dihydroflavonoid isolated from the ethanolic extract of Coreopsistinctoria and is considered to be one of the active ingredients of the herb with a wide range of pharmacological effects, but there are not many studies on the in vitro and in vivo pharmacokinetics of flavanomarein.

The Uses of Flavanomarein

Flavanomarein is a predominant flavonoid of Coreopsis tinctoria Nutt with protective effects against diabetic nephropathy. Flavanomarein has good antioxidative, antidiabetic, antihypertensive and anti-hyperlipidemic activities.
Flavanomarein inhibits high glucose-stimulated epithelialmesenchymal transition in HK-2 cells via targeting spleen tyrosine kinase

Properties of Flavanomarein

Melting point:	243-246°C
Boiling point:	818.2±65.0 °C(Predicted)
Density	1.665±0.06 g/cm3(Predicted)
pka	7.58±0.40(Predicted)
form	Solid
color	White to off-white

Safety information for Flavanomarein

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P271:Use only outdoors or in a well-ventilated area.