FDG
Synonym(s):FDG
- CAS NO.:17817-20-8
- Empirical Formula: C32H32O15
- Molecular Weight: 656.59
- MDL number: MFCD00077344
- EINECS: 1312995-182-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 16:48:35
What is FDG?
The Uses of FDG
For detecting Glycosidases and could be used in ELISAs, FDG substrate has also been used for identifying lacZ-positive cells with fluorescence microscopy and flow cytometry
The Uses of FDG
Ultra sensitive fluorogenic substrate for ?-galactosidase, used in live cell and tissue (in vivo and in vitro) assays. This fluorescent substrate reagent could be used for monitoring kinetics of hydrolysis.
The Uses of FDG
Fluorescein di(β-D-galactopyranoside) (FDG) has been used for the detection of gene expression via FACS (fluorescence-activated cell sorting).
What are the applications of Application
Fluorescein di(β-D-galactopyranoside) is a fluorogenic substrate for β-galactosidase
Biochem/physiol Actions
Fluorescein di (β-D-galactopyranoside) (FDG) results in fluorescence after being hydrolyzed to fluorescein by β-galactosidase. It gives fluorescence proportional to the enzymatic activity. This molecule is mainly required for the detection of gene expression in transfected cells when using β-galactosidase (Lac Z) as a reporter gene.
Properties of FDG
Melting point: | 200-203 °C (dec.) |
Boiling point: | 974.8±65.0 °C(Predicted) |
Density | 1.74±0.1 g/cm3(Predicted) |
storage temp. | -20°C |
solubility | DMSO: soluble |
form | A solid |
pka | 12.44±0.70(Predicted) |
color | Yellow to orange |
Safety information for FDG
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for FDG
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