ETHYL TRANS-4-OXO-2-BUTENOATE

CAS NO.：2960-66-9
Empirical Formula: C6H8O3
Molecular Weight: 128.13
MDL number: MFCD00236170
EINECS: 1592732-453-0
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-06 15:28:16

What is ETHYL TRANS-4-OXO-2-BUTENOATE?

Chemical properties

Clear yellow-green liquid

The Uses of ETHYL TRANS-4-OXO-2-BUTENOATE

Ethyl trans-4-oxo-2-butenoate is an intermediate used to synthesize pharmaceutically active molecules. It is also used in the asymmetric catalytic alkynylation of acetaldehyde, producing attractive synthons with broad applications, such as (+)-Tetrahydropyrenophorol.

What are the applications of Application

Ethyl trans-4-oxo-2-butenoate is an intermediate used to synthesize pharmaceutically active molecules

Synthesis Reference(s)

The Journal of Organic Chemistry, 49, p. 3421, 1984 DOI: 10.1021/jo00192a047
Synthetic Communications, 18, p. 1913, 1988 DOI: 10.1080/00397918808068257
Tetrahedron Letters, 31, p. 2145, 1990 DOI: 10.1016/0040-4039(90)80094-3

Properties of ETHYL TRANS-4-OXO-2-BUTENOATE

Melting point:	-9°C
Boiling point:	184-188°C
Density	1,063 g/cm³
refractive index	1.4550
Flash point:	68°C
storage temp.	Inert atmosphere,Store in freezer, under -20°C
Water Solubility	Slightly soluble in water(2.6 g/L at 25°C).
BRN	8762336

Safety information for ETHYL TRANS-4-OXO-2-BUTENOATE

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Skull and Crossbones Acute Toxicity GHS06
GHS Hazard Statements	H227:Flammable liquids H301:Acute toxicity,oral H314:Skin corrosion/irritation H317:Sensitisation, Skin H318:Serious eye damage/eye irritation
Precautionary Statement Codes	P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.