Ethyl trans-2-[4-(Boc-aMino)cyclohexyl]acetate

CAS NO.：946598-34-1
Empirical Formula: C15H27NO4
Molecular Weight: 285.38
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-12 11:12:40

What is Ethyl trans-2-[4-(Boc-aMino)cyclohexyl]acetate?

The Uses of Ethyl trans-2-[4-(Boc-aMino)cyclohexyl]acetate

Ethyl 2-((1R,4R)-4-((tert-Butoxycarbonyl)amino)cyclohexyl)acetate is an intermediate for the synthesis of Desmethyl Cariprazine Hydrochloride (D291365), a derivative of Cariprazine (C183490) which is an orally active D2/D3 dopamine receptor antagonist (1,2,3). Cariprazine is an antipsychotic drug candidate for the potential treatment of schizophrenia, bipolar mania and depression.

Properties of Ethyl trans-2-[4-(Boc-aMino)cyclohexyl]acetate

Melting point:	75 °C
Boiling point:	378.0±11.0 °C(Predicted)
Density	1.04±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
form	powder to crystal
pka	12.50±0.40(Predicted)
color	White to Almost white

Safety information for Ethyl trans-2-[4-(Boc-aMino)cyclohexyl]acetate

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P362:Take off contaminated clothing and wash before reuse. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention.