Ethyl propionylacetate
Synonym(s):Ethyl 3-oxovalerate
- CAS NO.：4949-44-4
- Empirical Formula: C7H12O3
- Molecular Weight: 144.17
- MDL number: MFCD00009317
- EINECS: 225-593-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-09 17:25:53
What is Ethyl propionylacetate?
Chemical properties
colourless liquid
The Uses of Ethyl propionylacetate
Ethyl propionylacetate acts as a precursor used in the preparation of 1-ethyl- and 1-n-propyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid bearing one or two substituents on the benzene ring. Further, it is used to prepare 3-propionyl-2H-cyclohepta[b]furan-2-one.
The Uses of Ethyl propionylacetate
An intermediate of Rosuvastatin.
The Uses of Ethyl propionylacetate
Ethyl propionylacetate has been used in the synthesis of 1-ethyl- and 1-n-propyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid bearing one or two substituents on the benzene ring.
What are the applications of Application
Ethyl 3-oxovalerate is an intermediate of Rosuvastatin.
Synthesis Reference(s)
Synthesis, p. 829, 1978 DOI: 10.1055/s-1978-24903
General Description
Ethyl propionylacetate reacts with tropolone p-toluenesulfonate in the presence of sodium ethoxide to give 3-propionyl-2H-cyclohepta[b]furan-2-one.
Properties of Ethyl propionylacetate
| Melting point: | 98 °C |
| Boiling point: | 83-84 °C/12 mmHg (lit.) |
| Density | 1.012 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 172 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Miscible with glacial acetic acid. |
| form | Liquid |
| pka | 10.58±0.46(Predicted) |
| Specific Gravity | 1.01 |
| color | Clear colorless to pale yellow |
| BRN | 970270 |
| Stability: | Stable. Combustible. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 4949-44-4(CAS DataBase Reference) |
| NIST Chemistry Reference | Ethyl propionylacetate(4949-44-4) |
Safety information for Ethyl propionylacetate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H227:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P370+P378:In case of fire: Use … for extinction. P405:Store locked up. P403+P235:Store in a well-ventilated place. Keep cool. P501:Dispose of contents/container to..… |
Computed Descriptors for Ethyl propionylacetate
| InChIKey | UDRCONFHWYGWFI-UHFFFAOYSA-N |
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
![Phosphonium, [[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]me](https://img.chemicalbook.in/CAS/GIF/885477-83-8.gif)
You may like
-
Ethyl propionylacetate 98% (GC) CAS 4949-44-4View Details
4949-44-4 -
Ethyl 3-Oxovalerate CAS 4949-44-4View Details
4949-44-4 -
Ethyl propionylacetate 97% CAS 4949-44-4View Details
4949-44-4 -
Ethyl propionylacetate CAS 4949-44-4View Details
4949-44-4 -
1823368-42-8 98%View Details
1823368-42-8 -
2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%View Details
1307449-08-6 -
Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 25408-95-1 98%View Details
25408-95-1 -
Lithium ClavulanateView Details
61177-44-4
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.