ETHYL PHENYLCYANOACETATE

CAS NO.：4553-07-5
Empirical Formula: C11H11NO2
Molecular Weight: 189.21
MDL number: MFCD00001866
EINECS: 224-921-4
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is ETHYL PHENYLCYANOACETATE?

Chemical properties

clear colorless to light yellow liquid

The Uses of ETHYL PHENYLCYANOACETATE

Ethyl phenylcyanoacetate?is a reagent used for the asymmetric synthesis of?(-)-manzacidin A.?It is also a useful reagent for C-C bond formation by conjugate additions with vinyl sulfones.

Definition

ChEBI: An alpha-substituted cyanoacetate ester that consists of ethyl cyanoacetate bearing an alpha-phenyl substituent.

Synthesis Reference(s)

Journal of the American Chemical Society, 64, p. 576, 1942 DOI: 10.1021/ja01255a033
Organic Syntheses, Coll. Vol. 4, p. 461, 1963
Synthesis, p. 67, 1983

Properties of ETHYL PHENYLCYANOACETATE

Melting point:	115-116 °C
Boiling point:	275 °C (lit.)
Density	1.09 g/mL at 25 °C (lit.)
refractive index	1.5033-1.5053
Flash point:	>110°C
storage temp.	Inert atmosphere,Room Temperature
solubility	Chloroform, DMSO, Methanol (Slightly)
form	Liquid
color	Clear colorless to light yellow
BRN	611232
CAS DataBase Reference	4553-07-5(CAS DataBase Reference)

Safety information for ETHYL PHENYLCYANOACETATE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.