ETHYL MANDELATE

Synonym(s):Ethyl α-hydroxyphenylacetate, Mandelic acid ethyl ester;Ethyl mandelate

CAS NO.：4358-88-7
Empirical Formula: C10H12O3
Molecular Weight: 180.2
MDL number: MFCD00004494
EINECS: 610-127-9
SAFETY DATA SHEET (SDS)
Update Date: 2024-04-28 15:15:04

What is ETHYL MANDELATE?

Chemical properties

Appearance :white solid or liquid

The Uses of ETHYL MANDELATE

Ethyl Mandelate is used as a reagent in the synthesis of several organic compounds including that of volatile methylsiloxanes which have the potential to be a more environmentally sustainable alternative as solvents in chemical synthesis to non-polar organic solvents. It was found to act as a substrate for (S)-mandelate dehydrogenase which is a flavin mononucleotide dependent enzyme that oxidises (S)-mandelate to benzoylformate.

Definition

ChEBI: Ethyl hydroxy(phenyl)acetate is the ethyl ester of mandelic acid. It is an ethyl ester and a secondary alcohol. It is functionally related to a mandelic acid.

Synthesis Reference(s)

Journal of the American Chemical Society, 107, p. 3981, 1985 DOI: 10.1021/ja00299a038
The Journal of Organic Chemistry, 49, p. 3241, 1984 DOI: 10.1021/jo00191a048

Properties of ETHYL MANDELATE

Melting point:	35.5°C
Boiling point:	253-255 °C(lit.)
alpha	[α]D20 -0.1～+0.2° (neat)
Density	1.115 g/mL at 25 °C(lit.)
refractive index	n20/D 1.512(lit.)
Flash point:	>230 °F
storage temp.	Refrigerator
solubility	Chloroform (Slightly), Ethyl Acetate (Slightly)
form	Oil
color	Colourless
CAS DataBase Reference	4358-88-7(CAS DataBase Reference)