Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name listEthyl Biscoumacetate

Ethyl Biscoumacetate

  • CAS NO.:548-00-5
  • Empirical Formula: C22H16O8
  • Molecular Weight: 408.36
  • MDL number: MFCD00128073
  • EINECS: 208-940-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-04-23 13:52:06
Ethyl Biscoumacetate Structural

What is Ethyl Biscoumacetate?

Chemical properties

White, crystalline solid; odorless; bitter taste.Soluble in acetone and benzene; slightly soluble in alcohol and ether; insoluble in water.

Originator

Tromexan,Geigy,US,1950

The Uses of Ethyl Biscoumacetate

Medicine (anticoagulant).

The Uses of Ethyl Biscoumacetate

Anticoagulant.

What are the applications of Application

Ethyl Biscoumacetate is a coumarin used as an anticoagulant

Definition

A synthetic derivative of bishydroxycoumarin.

Manufacturing Process

7 g of benzotetronic acid are dissolved in 750 cc of water at boiling temperature and there after 10.5 g of glyoxylic acid ethyl ester ethyl alcoholate are added. After a short while the liquid becomes turbid and gradually a white deposit is separated. The deposit is filtrated and dried in vacuo. The melting point is 172°C to 174°C; after recrystallization from methyl alcohol 153°C to 154°C.
The crude product is dissolved in sodium lye, filtrated by means of animal charcoal precipitated by means of hydrochloric acid, and recrystallized from methyl alcohol. The melting point is 153°C to 154°C.

Therapeutic Function

Anticoagulant

Synthesis

Ethyl biscoumacetate, the ethyl ester of bis-(4-hydroxy- 3-coumarinyl)-acetic acid (24.1.9), is synthesized analogously from 4-hydroxycoumarine, but using ethylglyoxylate, its semiacetal or glyoxylic acid instead of formaldehyde.

Synthesis_548-00-5

Properties of Ethyl Biscoumacetate

Melting point: 177-182° and mp 154-157°
Boiling point: 448.92°C (rough estimate)
Density  1.3259 (rough estimate)
refractive index  1.4480 (estimate)
storage temp.  Amber Vial, -20°C Freezer, Under inert atmosphere
solubility  Chloroform (Slightly), DMSO (Slightly)
form  Solid
pka pKa 7.5 (Uncertain)
color  White
Water Solubility  54.31mg/L(temperature not stated)

Safety information for Ethyl Biscoumacetate

Computed Descriptors for Ethyl Biscoumacetate

Related products of tetrahydrofuran

You may like

Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.