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HomeProduct name listETHYL 3-(N-METHYLAMINO) PROPIONATE

ETHYL 3-(N-METHYLAMINO) PROPIONATE

ETHYL 3-(N-METHYLAMINO) PROPIONATE Structural

What is ETHYL 3-(N-METHYLAMINO) PROPIONATE?

The Uses of ETHYL 3-(N-METHYLAMINO) PROPIONATE

Ethyl N-Methyl-beta-alaninate is an intermediate in the synthesis of Tolafentrine (T531000), which is a dual-selective phosphodiesterase 3/4 inhibitor used in chronic experimental pulmonary hypertension.

Synthesis Reference(s)

Journal of the American Chemical Society, 71, p. 2124, 1949 DOI: 10.1021/ja01174a061

Properties of ETHYL 3-(N-METHYLAMINO) PROPIONATE

Boiling point: 242.49°C (rough estimate)
Density  1.0070
refractive index  1.4443 (estimate)
storage temp.  Inert atmosphere,Store in freezer, under -20°C
solubility  Chloroform (Sparingly), Ethyl Acetate (Slightly)
form  Oil
pka 9.55±0.10(Predicted)
color  Colourless

Safety information for ETHYL 3-(N-METHYLAMINO) PROPIONATE

Computed Descriptors for ETHYL 3-(N-METHYLAMINO) PROPIONATE

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