Ethyl 3-methyl-2-oxobutyrate

Synonym(s):Ethyl dimethylpyruvate;Ketovaline ethyl ester

CAS NO.：20201-24-5
Empirical Formula: C7H12O3
Molecular Weight: 144.17
MDL number: MFCD00009122
EINECS: 243-587-0
SAFETY DATA SHEET (SDS)
Update Date: 2024-02-29 17:14:10

What is Ethyl 3-methyl-2-oxobutyrate?

Chemical properties

clear light yellow liquid

The Uses of Ethyl 3-methyl-2-oxobutyrate

Ethyl 3-methyl-2-oxobutyrate was used in the synthesis of (2SR,4SR)-5(S)-(N-Boc)-amino-6-cyclohexyl-4-hydoxy-2-isopropyl hexanoic acid.

The Uses of Ethyl 3-methyl-2-oxobutyrate

Ethyl dimethylpyruvate is used as an allyl halide reactant in the presence of indium to release hydroxy unsaturated carbonyl compounds. It was also used in the synthesis of (2SR,4SR)-5(S)-(N-Boc)-amino-6-cyclohexyl-4-hydoxy-2-isopropyl hexanoic acid.

What are the applications of Application

Ethyl 3-methyl-2-oxobutyrate is An allyl halide reactant in the presence of indium to release hydroxy unsaturated carbonyl compounds

General Description

Ethyl 3-methyl-2-oxobutyrate reacts with a variety of allyl halides in the presence of indium to afford hydroxy unsaturated carbonyl compounds. Conformational behaviour of ethyl 3-methyl-2-oxobutyrate was investigated using solution FTIR in combination with ab initio calculations.

Properties of Ethyl 3-methyl-2-oxobutyrate

Boiling point:	62 °C/11 mmHg (lit.)
Density	0.989 g/mL at 25 °C (lit.)
refractive index	n20/D 1.410(lit.)
Flash point:	110 °F
storage temp.	2-8°C
form	Liquid
color	Clear light yellow
Water Solubility	Slightly soluble in water.
BRN	1756668
InChI	InChI=1S/C7H12O3/c1-4-10-7(9)6(8)5(2)3/h5H,4H2,1-3H3

Safety information for Ethyl 3-methyl-2-oxobutyrate

Signal word	Warning
Pictogram(s)	Flame Flammables GHS02
GHS Hazard Statements	H226:Flammable liquids
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P241:Use explosion-proof electrical/ventilating/lighting/…/equipment. P242:Use only non-sparking tools. P243:Take precautionary measures against static discharge.