ETHYL 2-(BROMOMETHYL)ACRYLATE

Synonym(s):2-(Bromomethyl)acrylic acid ethyl ester;Ethyl α-(bromomethyl)acrylate;Ethyl 2-(bromomethyl)-2-propenoate;Ethyl 2-(bromomethyl)propenoate

CAS NO.：17435-72-2
Empirical Formula: C6H9BrO2
Molecular Weight: 193.04
MDL number: MFCD00031518
EINECS: 628-033-1
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

ETHYL 2-(BROMOMETHYL)ACRYLATE Structural

What is ETHYL 2-(BROMOMETHYL)ACRYLATE?

Chemical properties

Colourless Oil

The Uses of ETHYL 2-(BROMOMETHYL)ACRYLATE

ETHYL 2-(BROMOMETHYL)ACRYLATE is an intermediate used for the synthesis of aza inhibitors of chorismate mutase.

The Uses of ETHYL 2-(BROMOMETHYL)ACRYLATE

It can be employed as an electrophile for various organometallic compounds. The organometallic derivatives of the compound can be used for the synthesis of α-methylene lactones and lactams. It can also be used for the polymerization of functionalized acrylic monomers.

What are the applications of Application

Ethyl Bromomethacrylate is An intermediate in the synthesis of aza inhibitors

General Description

Ethyl 2-(bromomethyl)acrylate is an allylic alkylating reagent.

Purification Methods

If it contains some free acid, add H2O, cool, and neutralise with NaHCO3 until evolution of CO2 ceases. Extract the mixture with Et2O (3x) and dry the combined extracts (Na2SO4, 3hours). Evaporate Et2O and distil the ester collecting fraction b 39-40o/0.9mm and check spectra. [Preparation and NMR: Ramarajan et al. Org Synth Coll Vol VII 211 1990, Beilstein 2 IV 1541.]

Properties of ETHYL 2-(BROMOMETHYL)ACRYLATE

Melting point:	134-136℃
Boiling point:	38 °C/0.8 mmHg (lit.)
Density	1.398 g/mL at 25 °C (lit.)
refractive index	n20/D 1.479(lit.)
Flash point:	178 °F
storage temp.	-20°C
solubility	Chloroform (Sparingly), Ethyl Acetate (Slightly)
form	Liquid
color	Colorless to pale yellow
BRN	970108
CAS DataBase Reference	17435-72-2(CAS DataBase Reference)

Safety information for ETHYL 2-(BROMOMETHYL)ACRYLATE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.