Ethyl 2-bromoisobutyrate

Synonym(s):Ethyl 2-bromo-2-methylpropionate

CAS NO.：600-00-0
Empirical Formula: C6H11BrO2
Molecular Weight: 195.05
MDL number: MFCD00000123
EINECS: 209-980-6
SAFETY DATA SHEET (SDS)
Update Date: 2024-08-21 22:41:43

What is Ethyl 2-bromoisobutyrate?

Description

Ethyl 2-bromoisobutyrate is an organic compound used in organic synthesis as a catalyst or starting material. The compound has a strong halogen group and can undergo multiple reactions, making it useful in various chemical reactions. One application of this compound is synthesizing cationic polymers for antibacterial peptide mimicry. These polymers showed promising antimicrobial activity against various strains of bacteria.

Chemical properties

colourless to slightly yellow liquid

The Uses of Ethyl 2-bromoisobutyrate

Ethyl 2-bromoisobutyrate is used as an Atom Transfer Radical Polymerization (ATRP) initiator that will generate a polymer with an ethyl end group.

storage

Store in cool, dry conditions in a sealed container. Incompatible with oxidizing agents, acids, bases, reducing agents.

Properties of Ethyl 2-bromoisobutyrate

Boiling point:	65-67 °C11 mm Hg(lit.)
Density	1.329 g/mL at 25 °C(lit.)
refractive index	n20/D 1.444(lit.)
Flash point:	140 °F
storage temp.	2-8°C
form	Liquid
color	Clear colorless to light yellow
Water Solubility	Soluble in alcohol, ether. Insoluble in water.
BRN	1098947
Dielectric constant	7.9（20℃）
Stability:	Stable. Incompatible with acids, bases, reducing agents, oxidizing agents.
InChI	InChI=1S/C6H11BrO2/c1-4-9-5(8)6(2,3)7/h4H2,1-3H3
CAS DataBase Reference	600-00-0(CAS DataBase Reference)
NIST Chemistry Reference	Propanoic acid, 2-bromo-2-methyl-, ethyl ester(600-00-0)
EPA Substance Registry System	Ethyl 2-bromoisobutyrate (600-00-0)

Safety information for Ethyl 2-bromoisobutyrate

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H226:Flammable liquids H302:Acute toxicity,oral H318:Serious eye damage/eye irritation
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.