Ethyl 2-amino-1,3-thiazole-4-carboxylate

CAS NO.：5398-36-7
Empirical Formula: C6H8N2O2S
Molecular Weight: 172.2
MDL number: MFCD00619079
EINECS: 611-074-4
SAFETY DATA SHEET (SDS)
Update Date: 2024-03-04 08:47:27

What is Ethyl 2-amino-1,3-thiazole-4-carboxylate?

Chemical properties

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The Uses of Ethyl 2-amino-1,3-thiazole-4-carboxylate

Ethyl 2-Amino-1,3-thiazole-4-carboxylate is a chemical reagent used in the preparation fo SAR thiazolamino arylaminopyrimidines as anaplastic lymphoma kinase inhibitors. As well as in the synthesis of 4-bicyclick piperadine derivatives as potent stearoyl-CoA desaturase (SCD1) inhibitors in the treatment of cancer.

Properties of Ethyl 2-amino-1,3-thiazole-4-carboxylate

Melting point:	177 °C
Boiling point:	308.0±15.0 °C(Predicted)
Density	1.336±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	2.60±0.10(Predicted)
color	Pale Beige
λmax	284nm(MeOH)(lit.)
InChI	InChI=1S/C6H8N2O2S/c1-2-10-5(9)4-3-11-6(7)8-4/h3H,2H2,1H3,(H2,7,8)
CAS DataBase Reference	5398-36-7(CAS DataBase Reference)

Safety information for Ethyl 2-amino-1,3-thiazole-4-carboxylate

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.