ETHIRIMOL
- CAS NO.:23947-60-6
- Empirical Formula: C11H19N3O
- Molecular Weight: 209.29
- MDL number: MFCD00055519
- EINECS: 245-949-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-05 19:05:58
What is ETHIRIMOL?
The Uses of ETHIRIMOL
Ethirimol is a systemic fungicide with both protective and curative actions. It controls mainly powdery mildew (Erysiphe gmminis) on barley, wheat and oats. Ethirimol can be applied as a seed dressing, as a foliar spray or directly to the soil in the root zone.
The Uses of ETHIRIMOL
Ethirimol is a pyrimidine based fungicide with wide applications such as controlling leaf spot of sugar beet.
The Uses of ETHIRIMOL
Fungicide.
Definition
ChEBI: An aminopyrimidine that is 2-ethylaminopyrimidin-4-one carrying butyl and methyl substituents at positions 5 and 6 respectively. A fungicide first marketed in 1970 and used as a seed treatment for diseaases such as damping-off, it is not licensed for use w thin the European Union.
Metabolic pathway
Ethirimol is susceptible to photodegradation and it also degrades extensively in soil to yield CO2 and unextractable soil-bound residues. Metabolism in plants and animals is extensive to yield up to 16 metabolites. Elimination in animals was rapid following oral dosing. Metabolism in soil, plants and animals follows common pathways which include N-dealkylation, hydroxylation of the butyl group and conjugation.
Degradation
Ethirimol (1) is stable to hydrolytic degradation in buffered solutions at pH 5, 7 and 9 at 22°C. It degraded under aqueous photolysis test conditions with a half-life (DT50) of ca. 3 weeks. The primary photolytic degradation reactions include the opening of the pyrimidine ring to yield ethylguanidine (2), urea (3) and 4-butylpyrazolidine-3,5-dione (4) (Cavell et al., 1974c).
Properties of ETHIRIMOL
Melting point: | 159-160° |
Boiling point: | 348.66°C (rough estimate) |
Density | 1.2100 |
vapor pressure | 2.7 x 10-4 Pa at 25 °C |
refractive index | 1.5700 (estimate) |
storage temp. | -20°C Freezer |
solubility | Chloroform (Sparingly), Ethanol (Slightly), Methanol (Slightly) |
pka | 5 |
form | neat |
Water Solubility | 253 mg l-1 (pH 5.2), 150 mg l-1 (pH 7.3),
153 mg l-1 (pH 9.3) at 20 °C |
color | White to Off-White |
Merck | 13,3776 |
BRN | 882476 |
EPA Substance Registry System | Ethirimol (23947-60-6) |
Safety information for ETHIRIMOL
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H312:Acute toxicity,dermal |
Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P501:Dispose of contents/container to..… |
Computed Descriptors for ETHIRIMOL
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