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HomeProduct name listERYTHROSIN B

ERYTHROSIN B

Synonym(s):2′,4′,5′,7′-Tetraiodofluorescein disodium salt;Acid Red 51;Erythrosin extra bluish;Iodoeosin;Solvent Red 140

  • CAS NO.:16423-68-0
  • Empirical Formula: C20H9I4NaO5
  • Molecular Weight: 859.89
  • MDL number: MFCD00144257
  • EINECS: 240-474-8
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-01 13:17:44
ERYTHROSIN B Structural

What is ERYTHROSIN B?

Description

FD & C Red No. 3 is principally the disodium salt of the monohydrate of 9(ocarboxyphenyl)-6-hydroxy-2,4,5,7-tetraiodo-3H- xanthen-3-one.
The colorant is a brown powder that dissolves in water to give a solution red at neutrality, with a yellow-brown precipitate in acid, and with a red precipitate in base. When dissolved in concentrated sulfuric acid, it yields a brown-yellow solution that evolves iodine and a precipitate of the free acid when heated.
FD & C Red No. 3 is used in dietary supplements, confectionery products, dairy products, cherries, jellies, jams, dessert powders, canned fruit and vegetable products, fish products, condiment sauces and bakery goods.1 .

Chemical properties

red to brown powder

The Uses of ERYTHROSIN B

Erythrosin B (FD&C Red #3) is a colorant. It is not recommended for use below ph 5.0, being insoluble at ph 3–5 but being stable at ph 7 and 8. It has a solubility in water of 9 g/100 ml at 25°c. It has fair stability to oxidation and poor to fair stability to light, while having good stability in 10% sugar systems. It has exceptional clarity and brilliance, having a bluish pink hue with very good tinctorial strength. It has poor compatibility with food components and is used in candies and confections as well as cherry dyeing. The common name is erythrosine.

The Uses of ERYTHROSIN B

antibacterial

The Uses of ERYTHROSIN B

Erythrosine B is a derivative of fluorone and is used as a cherry-pink synthetic colour additives used on food products.

The Uses of ERYTHROSIN B

Biological stain; color additive.

What are the applications of Application

Erythrosin extra bluish is a dye used as a fluorescent indicator in microscopy and for adsorption

Definition

ChEBI: An organic sodium salt that is the disodium salt of 2-(2,4,5,7-tetraiodo-6-oxido-3-oxo-8a,10a-dihydroxanthen-9-yl)benzoic acid.

Preparation

fluorescent element (C.I. Acid Yellow 73, C.I. 45350) or ethanol in aqueous solution of the four iodine, then into sodium salt.

General Description

Erythrosin B (C.I. 45430)for microscopy Certistain?, is a dry dye for microscopy that is often used as a counterstain, vizualising proteins, connective tissues, fibers and keratin in sample material of human origin. Depending on user requirements and personal preferences, it can be used for the preparation of the commonly used aqueous or alcoholic Erythrosin B staining solutions. As the dye belongs to the portfolio of Certistain? dyes, it is chemically analyzed according to strict specifications before release (CE marked and IVD product) and a high staining quality, with reliable staining results is guaranteed. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.

Flammability and Explosibility

Not classified

Biochem/physiol Actions

Erythrosin B, also called as eosin B, is a xanthene dye. It belongs to the family of fluorescein dyes. Erythrosin B is an artificial food dye that induces hyperkinesis when swallowed by susceptible children. It plays a major role in inhibiting dopamine uptake and high affinity 3H-ouabain binding and ion transport in synaptosomes from rat caudate nucleus.

storage

Room temperature

Properties and Applications

blue light pink. Soluble in water is cherry red, no fluorescence. The strong sulfuric acid is palm in light yellow, diluted into palm yellow light precipitation. In water solution to join sodium hydroxide to create soluble red precipitate.

Standard Light Fastness Soaping Persperation Fastness Oxygen bleaching Fastness to seawater
Fading Stain Fading Stain Fading Stain
ISO 1 3 4 1 2-3

Properties of ERYTHROSIN B

Melting point: 142~144℃
Density  0.98
vapor pressure  0Pa at 25℃
Flash point: 285℃
storage temp.  room temp
solubility  100g/l
form  Fine Powder
Colour Index  45430
pka 4.1(at 25℃)
color  Deep red to brown
PH 6-7 (10g/l, H2O, 20℃)
PH Range 0(yellow)-3.6(red)
Water Solubility  Soluble in water
λmax 525nm
Merck  14,3693
BRN  1443945
Stability: Stable. Incompatible with strong oxidizing agents.
Biological Applications Detecting gene expression,phosphoproteins,protease,stress biomarkers; treating age-related macular degeneration,arteriosclerosis,bone metabolic diseases,burns,cancer,diabetes,human immunodeficiency virus infection,obesity
Major Application color filter, light emitting diodes, nanosensors, imaging materials, inks, paints, colored bubbles, detergents, cleaners, cosmetics, oral care agent, hair dyes, antiseptic, treatment of burns, diabetes, obesity, cancer, viral diseases, radio chemotheray, photodynamic therapy
CAS DataBase Reference 16423-68-0
EPA Substance Registry System Erythrosine B (16423-68-0)

Safety information for ERYTHROSIN B

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
ghs
Environment
GHS09
GHS Hazard Statements H302:Acute toxicity,oral
H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P273:Avoid release to the environment.
P391:Collect spillage. Hazardous to the aquatic environment
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501:Dispose of contents/container to..…

Computed Descriptors for ERYTHROSIN B

InChIKey RAGZEDHHTPQLAI-UHFFFAOYSA-L

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