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Ervamycine

Ervamycine Structural

What is Ervamycine?

Description

This alkaloid from Vinca herbacea has been isolated as the crystalline hydrochloride, m.p. 184-6°C (dec.). The free base has [α]23D - 310° ± 2° (c 0.32, CHC13). Hydrogenation over Pt02 gives the 6:7-dihydro derivative which has [α]26D - 412.8° (c 0.606, CHCI3). When heated at 100°C with 5N-HC1, the latter is simultaneously hydrolyzed and decarboxylated to furnish 16-methoxy- 1: 2-dehydro-( - )-aspidospermidine.

Definition

ChEBI: 16-methoxytabersonine is the 16-methoxy derivative of tabersonine. It is a monoterpenoid indole alkaloid, an organic heteropentacyclic compound, a methyl ester and a tertiary amino compound. It is functionally related to a tabersonine. It is a conjugate base of a 16-methoxytabersoninium(1+).

References

Pyuskyulev et al., Collect. Czech. Chem. Commun., 32, 1289 (1967)

Properties of Ervamycine

Boiling point: 514.6±50.0 °C(Predicted)
Density  1.27±0.1 g/cm3(Predicted)
pka 7.66±0.60(Predicted)

Safety information for Ervamycine

Computed Descriptors for Ervamycine

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