Eprazinone
- CAS NO.：10402-90-1
- Empirical Formula: C24H32N2O2
- Molecular Weight: 380.52
- MDL number: MFCD00866843
- EINECS: 233-873-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-23 13:36:13
What is Eprazinone?
Originator
Mucitux,Riom,France,1969
Definition
ChEBI: A member of the class of piperazines in which the two amino hydrogens of piperazine are replaced by 2-benzoylpropyl and 2-ethoxy-2-phenylethyl groups.
Manufacturing Process
61.4 g of 0.2M of 1-(2-phenyl-2-ethoxy)piperazine dihydrochloride, 33.5 g
(0.25M) propiophenone, 75 g (0.25M) trioxymethylene, 120 ml of ethanol and
0.4 ml of concentrated HCl are heated under reflux for 4 to 5 hours. The
product is allowed to crystallize, then filtered and washed with alcohol. It is
dried and recrystallized from methanol containing 10% H2O.
There is thus obtained 60 g of a white crystalline powder soluble in water.
Yield: 66%. Melting point: 160°C.
Therapeutic Function
Antitussive
Properties of Eprazinone
| Boiling point: | 508.13°C (rough estimate) |
| Density | 1.0909 (rough estimate) |
| refractive index | 1.5500 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 6.83±0.10(Predicted) |
| CAS DataBase Reference | 10402-90-1(CAS DataBase Reference) |
Safety information for Eprazinone
Computed Descriptors for Eprazinone
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