Epi-N-Quinyl-N’-bis(3,5-trifluoromethyl) phenylthiourea

Synonym(s):epi-N-Quinyl-N′-bis(3,5-trifluoromethyl)phenylthiourea;1-[3,5-Bis(trifluoromethyl)phenyl)-3-{(S)(6-methoxy-4-quinolinyl)-[(2S,4S,5R)-5-vinyl-1-aza-bicyclo[2.2.2]oct-2-yl]methyl}thiourea

CAS NO.：852913-16-7
Empirical Formula: C29H28F6N4OS
Molecular Weight: 594.61
MDL number: MFCD16875670
SAFETY DATA SHEET (SDS)
Update Date: 2022-08-15 17:39:34

Epi-N-Quinyl-N’-bis(3,5-trifluoromethyl)
phenylthiourea Structural

What is Epi-N-Quinyl-N’-bis(3,5-trifluoromethyl) phenylthiourea?

Chemical properties

Solid

The Uses of Epi-N-Quinyl-N’-bis(3,5-trifluoromethyl) phenylthiourea

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8a,9S)-6′-methoxy-9-cinchonanyl]thiourea is a bifunctional cinchona organocatalyst, which can be used to synthesize:

Stereoselective diaryl(nitro)butanone via enantioselective Michael addition of nitromethane to chalcones.
Enantioselective β-amino acids via asymmetric Mannich reaction of malonates with aryl and alkyl imines.
The synthesis of 3-indolylmethanamines by the reaction of indoles with imines via asymmetric Friedel-Crafts reaction.
The enantioselective conjugate addition of active methylene compounds to enones to obtain the corresponding addition products.

Properties of Epi-N-Quinyl-N’-bis(3,5-trifluoromethyl) phenylthiourea

Boiling point:	598.2±60.0 °C(Predicted)
Density	1.39±0.1 g/cm3(Predicted)
pka	11.39±0.70(Predicted)

Safety information for Epi-N-Quinyl-N’-bis(3,5-trifluoromethyl) phenylthiourea

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06
GHS Hazard Statements	H301:Acute toxicity,oral
Precautionary Statement Codes	P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.