Ecabet sodium

CAS NO.：86408-72-2
Empirical Formula: C20H29NaO5S
Molecular Weight: 404.5
MDL number: MFCD00866896
EINECS: 1312995-182-4
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-06 15:28:16

What is Ecabet sodium?

Description

Ecabet sodium is a new antiulcer agent launched in Japan for the treatment of gastric ulcer. It has both mucosal-protective and tissue-repairing properties. In rats, it effectively prevents gastrointestinal lesion formation induced experimentally by EtOH, HCl, NaOH, and boiling water. The mechanism of action has been suggested to involve inhibition of pepsin activity in gastric juice by precipitating pepsin in the form of a complex and inactivating pepsinogen.

Originator

Tanabe (Japan)

brand name

Gastrom

Properties of Ecabet sodium

Melting point:	>300°
alpha	D20 +59.4° (c = 0.5)
storage temp.	Store at -20°C
solubility	DMF: 25 mg/ml; DMSO: 30 mg/ml; Ethanol: 3 mg/ml; PBS (pH 7.2): 3 mg/ml
form	A crystalline solid
color	White to off-white

Safety information for Ecabet sodium

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H332:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.