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HomeProduct name listEcabet sodium

Ecabet sodium

  • CAS NO.:86408-72-2
  • Empirical Formula: C20H29NaO5S
  • Molecular Weight: 404.5
  • MDL number: MFCD00866896
  • EINECS: 1312995-182-4
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-05 19:05:58
Ecabet sodium Structural

What is Ecabet sodium?

Description

Ecabet sodium is a new antiulcer agent launched in Japan for the treatment of gastric ulcer. It has both mucosal-protective and tissue-repairing properties. In rats, it effectively prevents gastrointestinal lesion formation induced experimentally by EtOH, HCl, NaOH, and boiling water. The mechanism of action has been suggested to involve inhibition of pepsin activity in gastric juice by precipitating pepsin in the form of a complex and inactivating pepsinogen.

Originator

Tanabe (Japan)

brand name

Gastrom

Properties of Ecabet sodium

Melting point: >300°
alpha  D20 +59.4° (c = 0.5)
storage temp.  Store at -20°C
solubility  DMF: 25 mg/ml; DMSO: 30 mg/ml; Ethanol: 3 mg/ml; PBS (pH 7.2): 3 mg/ml
form  A crystalline solid
color  White to off-white

Safety information for Ecabet sodium

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H332:Acute toxicity,inhalation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Ecabet sodium

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