Dolutegravir Impurity 8
- CAS NO.:2244161-72-4
- Empirical Formula: C20H19F2N3O5
- Molecular Weight: 419.38
- Update Date: 2024-04-25 17:59:01
What is Dolutegravir Impurity 8?
The Uses of Dolutegravir Impurity 8
4-Desfluoro-6-fluoro Dolutegravir is impurity C of Dolutegravir (D528800), which is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.
Properties of Dolutegravir Impurity 8
Boiling point: | 664.9±55.0 °C(Predicted) |
Density | 1.53±0.1 g/cm3(Predicted) |
pka | 4.50±1.00(Predicted) |
Safety information for Dolutegravir Impurity 8
Computed Descriptors for Dolutegravir Impurity 8
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4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium THOMAIND PAPER PH 2.0 TO 4.5 1 BOX BUFFER CAPSULE PH 9.2 - 10 CAP SODIUM CHLORIDE 0.1N CVS ALLOXAN MONOHYDRATE 98% PLATINUM 0.5% ON 3 MM ALUMINA PELLETS (TYPE 73) LITHIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
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Dolutegravir Glucoside
Dolutegravir Impurity 14(Sodium Salt)
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Dolutegravir Glucuronide
Dolutegravir Impurity 15
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