DOCUSATE CALCIUM (500 MG)
Synonym(s):Bis(2-ethylhexyl) sulfosuccinate hemicalcium salt
- CAS NO.:128-49-4
- Empirical Formula: C20H40CaO7S
- Molecular Weight: 464.67
- EINECS: 204-889-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-09-06 17:45:48
What is DOCUSATE CALCIUM (500 MG)?
Originator
Surfak,Hoechst,US,1959
The Uses of DOCUSATE CALCIUM (500 MG)
Stool softener.
The Uses of DOCUSATE CALCIUM (500 MG)
Calcium salt of Docusate, used for the treatment of constipation, acting as a laxative or stool softener.
Manufacturing Process
88 g of dioctyl sodium sulfosuccinate is first dissolved in 100 cc of isopropanol and 25 g of calcium chloride is dissolved in 50 cc of methanol. The solutions are then mixed and stirred for about 3 hours and then cooled with ice. The sodium chloride which precipitates in the cool mixture is removed by filtration and most of the alcohol is evaporated from the resulting filtrate with heat. The liquid remaining is poured into 88 cc of water, and the resulting precipitate washed with water until free of chloride ion. The washed calcium salt is then dried.
brand name
Surfak (Hoechst-Roussel).
Therapeutic Function
Stool softener
Flammability and Explosibility
Non flammable
Properties of DOCUSATE CALCIUM (500 MG)
Boiling point: | 339℃[at 101 325 Pa] |
Density | 1.021[at 20℃] |
vapor pressure | 0Pa at 20℃ |
storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
solubility | DMSO (Slightly, Heated), Methanol (Slightly) |
form | Solid |
color | White to Off-White Sticky |
Water Solubility | 6g/L at 20℃ |
Stability: | Hygroscopic |
Safety information for DOCUSATE CALCIUM (500 MG)
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for DOCUSATE CALCIUM (500 MG)
Abamectin manufacturer
Badrivishal Chemicals Pharmaceuticals
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