DOCUSATE CALCIUM (500 MG)

Synonym(s):Bis(2-ethylhexyl) sulfosuccinate hemicalcium salt

CAS NO.：128-49-4
Empirical Formula: C20H40CaO7S
Molecular Weight: 464.67
EINECS: 204-889-8
SAFETY DATA SHEET (SDS)
Update Date: 2023-09-06 17:45:48

What is DOCUSATE CALCIUM (500 MG)?

Originator

Surfak,Hoechst,US,1959

The Uses of DOCUSATE CALCIUM (500 MG)

Stool softener.

The Uses of DOCUSATE CALCIUM (500 MG)

Calcium salt of Docusate, used for the treatment of constipation, acting as a laxative or stool softener.

Manufacturing Process

88 g of dioctyl sodium sulfosuccinate is first dissolved in 100 cc of isopropanol and 25 g of calcium chloride is dissolved in 50 cc of methanol. The solutions are then mixed and stirred for about 3 hours and then cooled with ice. The sodium chloride which precipitates in the cool mixture is removed by filtration and most of the alcohol is evaporated from the resulting filtrate with heat. The liquid remaining is poured into 88 cc of water, and the resulting precipitate washed with water until free of chloride ion. The washed calcium salt is then dried.

brand name

Surfak (Hoechst-Roussel).

Therapeutic Function

Stool softener

Flammability and Explosibility

Non flammable

Properties of DOCUSATE CALCIUM (500 MG)

Boiling point:	339℃[at 101 325 Pa]
Density	1.021[at 20℃]
vapor pressure	0Pa at 20℃
storage temp.	Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility	DMSO (Slightly, Heated), Methanol (Slightly)
form	Solid
color	White to Off-White Sticky
Water Solubility	6g/L at 20℃
Stability:	Hygroscopic

Safety information for DOCUSATE CALCIUM (500 MG)

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention.