Diethyl (hydroxymethyl)phosphonate

Synonym(s):(Hydroxymethyl)phosphonic acid diethyl ester;Diethyl phosphonomethanol

CAS NO.：3084-40-0
Empirical Formula: C5H13O4P
Molecular Weight: 168.13
MDL number: MFCD00014418
EINECS: 221-391-6
SAFETY DATA SHEET (SDS)
Update Date: 2025-01-27 09:38:02

Diethyl (hydroxymethyl)phosphonate Structural

What is Diethyl (hydroxymethyl)phosphonate?

Chemical properties

Clear colorless to yellow viscous liquid

The Uses of Diethyl (hydroxymethyl)phosphonate

Diethyl hydroxymethylphosphonate acts as a reactant for synthesis of α And β-dialkoxyphosphoryl isothiocyanate used in antiproliferative studies, dendritic polyglycerol anions for L-selectin inhibition, phosphonates for anti-HIV-1 activity, homo and copolymers of phosphonated norbornenes, Mitsunobu reactions. It is involved in studies of FBPase inhibition by phosphonic acid-containing thaizoles.

Properties of Diethyl (hydroxymethyl)phosphonate

Boiling point:	124-126 °C/3 mmHg (lit.)
Density	1.14 g/mL at 25 °C (lit.)
refractive index	n20/D 1.444(lit.)
Flash point:	>230 °F
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
form	Viscous Liquid
pka	13.00±0.10(Predicted)
color	Clear colorless to yellow
Water Solubility	500g/L at 20℃
CAS DataBase Reference	3084-40-0(CAS DataBase Reference)
NIST Chemistry Reference	Diethyl hydroxymethylphosphonate(3084-40-0)
EPA Substance Registry System	Phosphonic acid, (hydroxymethyl)-, diethyl ester (3084-40-0)

Safety information for Diethyl (hydroxymethyl)phosphonate

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.