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HomeProduct name listDIETHYL 5-AMINO-3-METHYL-2,4-THIOPHENEDICARBOXYLATE

DIETHYL 5-AMINO-3-METHYL-2,4-THIOPHENEDICARBOXYLATE

  • CAS NO.:4815-30-9
  • Empirical Formula: C11H15NO4S
  • Molecular Weight: 257.31
  • MDL number: MFCD00005450
  • EINECS: 225-388-0
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-04-23 13:52:06
DIETHYL 5-AMINO-3-METHYL-2,4-THIOPHENEDICARBOXYLATE Structural

What is DIETHYL 5-AMINO-3-METHYL-2,4-THIOPHENEDICARBOXYLATE?

Chemical properties

slightly yellow to beige-yellow crystalline powder

The Uses of DIETHYL 5-AMINO-3-METHYL-2,4-THIOPHENEDICARBOXYLATE

Diethyl 5-Amino-3-methylthiophene-2,4-dicarboxylate is used as a reagent in the synthesis of novel pyrazolo-pyrimidinones as dipeptidyl peptidase IV (DPP-IV) inhibitors in diabetes. It is also used in the synthesis of N-phenylthieno[2,3-d]pyrimidin-4-amines which act as inhibitors of fibroblast grow factor receptor 1 and therefore may be further used as anticancer agents.

Properties of DIETHYL 5-AMINO-3-METHYL-2,4-THIOPHENEDICARBOXYLATE

Melting point: 105-108 °C(lit.)
Boiling point: 372.6±37.0 °C(Predicted)
Density  1.3137 (rough estimate)
refractive index  1.5500 (estimate)
pka -0.53±0.10(Predicted)
form  Crystalline Powder
color  Slightly yellow to beige-yellow
CAS DataBase Reference 4815-30-9(CAS DataBase Reference)

Safety information for DIETHYL 5-AMINO-3-METHYL-2,4-THIOPHENEDICARBOXYLATE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405:Store locked up.

Computed Descriptors for DIETHYL 5-AMINO-3-METHYL-2,4-THIOPHENEDICARBOXYLATE

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