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HomeProduct name listDEHYDRO ARIPIPRAZOLE

DEHYDRO ARIPIPRAZOLE

Synonym(s):7-{4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butoxy}quinolin-2(1H)-one;Dehydroaripiprazole

DEHYDRO ARIPIPRAZOLE Structural

What is DEHYDRO ARIPIPRAZOLE?

The Uses of DEHYDRO ARIPIPRAZOLE

Dehydro Aripiprazole (Aripiprazole EP Impurity E; Aripiprazole USP Related Compound G) is an impurity of Aripiprazole (A771000), a selective dopamine D2-receptor antagonist with dopamine autoreceptor agonist activity.

General Description

Dehydro Aripiprazole is the primary, active metabolite of aripiprazole, marketed as the atypical antipsychotic Abilify? for the treatment of schizophrenia, bipolar disorder, and clinical depression. This new certified solution standard is suitable for use in LC or GC applications including forensic or clinical toxicology analysis and urine drug testing.

Properties of DEHYDRO ARIPIPRAZOLE

Melting point: >139oC (dec.)
Boiling point: 654.4±55.0 °C(Predicted)
Density  1.281±0.06 g/cm3(Predicted)
Flash point: 349℃
storage temp.  2-8°C
solubility  Chloroform (Slightly), Methanol (Slightly, Heated)
form  Solid
pka 11.22±0.70(Predicted)
color  White to Off-White

Safety information for DEHYDRO ARIPIPRAZOLE

Signal word Danger
Pictogram(s)
ghs
Flame
Flammables
GHS02
ghs
Corrosion
Corrosives
GHS05
ghs
Skull and Crossbones
Acute Toxicity
GHS06
ghs
Health Hazard
GHS08
GHS Hazard Statements H225:Flammable liquids
H290:Corrosive to Metals
H370:Specific target organ toxicity, single exposure
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233:Keep container tightly closed.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

Computed Descriptors for DEHYDRO ARIPIPRAZOLE

InChIKey CDONPRYEWWPREK-UHFFFAOYSA-N

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