DBCO-S-S-SE
Synonym(s):DBCO-S-S-NHS ester;DBCO-S-S-SE;DBCO-S-S-succinimidyl ester
- Molecular Weight: 0
- MDL number: MFCD22380758
What is DBCO-S-S-SE?
The Uses of DBCO-S-S-SE
Cleavable succinimidyl ester/NHS functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into amine containing compounds or biomolecules. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage. The disulfide present can be readily cleaved using mild reducing conditions (10-50 mM DTT at 37°C for 30 min or 5% ?-mercaptoethanol in SDS-PAGE sample buffer at 100°C for 5 minutes).
Caution: Please avoid reducing agents and amine or azide containing buffers during coupling/labeling reactions. Only use reducing agents when cleavage of the disulfide is desired.
Properties of DBCO-S-S-SE
Melting point: | 192-197 °C |
storage temp. | -20°C |
Safety information for DBCO-S-S-SE
Computed Descriptors for DBCO-S-S-SE
New Products
Tubulysin C Tubulysin I Tubulysin F Potassium HMDS (1.0 M in THF) Diethyl Aluminium Cyanide (1.0 M in Toluene) CYCLOBUTYLAMINE HYDROCHLORIDE 4,4-DIFLUOROPIPERIDINE tetrahydro-4-methyl-2H-pyran 1,2,3,6-TETRAHYDROPYRIDINE HYDROCHLORIDE 4-(Benzyloxy)-3-bromophenylacetic Acid 3-Aminocyclobutanone hydrochloride 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile Fuel shell Calcium Sodium Phosphosilicate IH Imeglimin Hydrochloride IH Latanoprostene Bunod Magnesium Trisilicate Lubiprostone Flame Retardant Zinc Borate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonate methyl 3-fluoro-4- thiomorpholino phenylcarbamate 7-Methoxyquinoline-4-carboxylic acidRelated products of tetrahydrofuran
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