D-ERYTHRONOLACTONE

Synonym(s):(3R-cis) (−)-Dihydro-3,4-dihydroxy-2(3H)-furanone;D-Erythronic acid γ-lactone;D-Erythronolactone

CAS NO.：15667-21-7
Empirical Formula: C4H6O4
Molecular Weight: 118.09
MDL number: MFCD00077763
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-04 17:34:34

What is D-ERYTHRONOLACTONE?

Chemical properties

D-ERYTHRONOLACTONE is white to light yellow crystal powde

The Uses of D-ERYTHRONOLACTONE

D-ERYTHRONOLACTONE is a chiral synthon used for the synthesis of certain natural products such as the leukotrienes

The Uses of D-ERYTHRONOLACTONE

D-erythrono-1,4-lactone is a potential substrates of dihydroxy acid dehydratase.

The Uses of D-ERYTHRONOLACTONE

A chiral synthon used for the synthesis of certain natural products such as the leukotrienes.

What are the applications of Application

D-Erythronolactone is a chiral synthon used to create analogs of certain natural products

Definition

ChEBI: Erythrono-1,4-lactone is a butan-4-olide that is dihydrofuran-2-one substituted at C-3 and C-4 by hydroxy groups (the 3R,4R-diastereomer). It is a butan-4-olide and a diol.

Purification Methods

Recrystallise it from EtOAc (20 parts) or isoPrOH (3 parts). [Baker & MacDonald J Am Chem Soc 82 230 1960, Glattfeld & Forbrich J Am Chem Soc 56 1209 1934, Weidenhagen & Wegner Chem Ber 72 2010 1939, Musich & Rapoport J Am Chem Soc 100 4865 1978, Beilstein 18/2 V 457.]

Properties of D-ERYTHRONOLACTONE

Melting point:	100-102 °C(lit.)
Boiling point:	140.59°C (rough estimate)
Density	1.0887 (rough estimate)
refractive index	-71 ° (C=1, H2O)
storage temp.	Sealed in dry,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	12.34±0.40(Predicted)
color	White to Off-White
optical activity	[α]20/D 71°, c = 1 in H2O
BRN	81073
CAS DataBase Reference	15667-21-7(CAS DataBase Reference)

Safety information for D-ERYTHRONOLACTONE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection.