Cyclooctylamine

Synonym(s):Aminocyclooctane

CAS NO.：5452-37-9
Empirical Formula: C8H17N
Molecular Weight: 127.23
MDL number: MFCD00001748
EINECS: 226-694-7
SAFETY DATA SHEET (SDS)
Update Date: 2023-10-21 17:17:25

What is Cyclooctylamine?

Chemical properties

clear colorless to light yellow liquid

The Uses of Cyclooctylamine

Cyclooctylamine is used as pharmaceutical intermediates.

Production Methods

Cyclooctylamine can be produced by the Ritter reaction of cyclooctanol with hydrocyanic acid, by reduction of cyclooctanone oxime with sodium and an alcohol, by Ritter reaction of cyclooctene with hydrocyanic acid, or by catalytic hydrogenation of cyclooctanone under amination conditions.

Properties of Cyclooctylamine

Melting point:	-48 °C (lit.)
Boiling point:	190 °C (lit.)
Density	0.928 g/mL at 25 °C (lit.)
refractive index	n20/D 1.482(lit.)
Flash point:	145 °F
storage temp.	Store below +30°C.
solubility	10.2g/l
form	Liquid
pka	11.03±0.20(Predicted)
color	Clear colorless to light yellow
PH	11.5 (4g/l, H2O, 20℃)
Water Solubility	Soluble in water. 10.2 g/L at 20°C.
BRN	2689120
CAS DataBase Reference	5452-37-9(CAS DataBase Reference)
NIST Chemistry Reference	Cyclooctanamine(5452-37-9)
EPA Substance Registry System	Cyclooctanamine (5452-37-9)

Safety information for Cyclooctylamine

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05
GHS Hazard Statements	H314:Skin corrosion/irritation
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.