Cremophor EL

Synonym(s):Cremophor EL;Cremophor ELP;Macrogolglycerol ricinoleate;PEG-35 castor oil;Polyoxyl-35 castor oil

CAS NO.：61791-12-6
Empirical Formula: NULL
Molecular Weight: 0
MDL number: MFCD00130879
EINECS: 500-151-7
Update Date: 2024-11-13 11:39:26

What is Cremophor EL?

Chemical properties

light yellow liquid

The Uses of Cremophor EL

Polyoxyl 35 Castor Oil is a triglyceride fatty acid which has the potential to repel insects and promote plant growth.

The Uses of Cremophor EL

Kolliphor^? EL has been used as a detergent to improve the solubility of dye and to increase the transmembrane permeation. It has been used as a vehicle for drug/stimulant delivery in cells.

General Description

Kolliphor^? EL is a nonionic solubilizer and emulsifier made by reacting castor oil with ethylene oxide. It is a pale yellow oily liquid that is clear at temperatures above 26°C. It has a faint but characteristic odour.

Flammability and Explosibility

Not classified

Biochem/physiol Actions

Kolliphor? EL is used in lipid-based formulations for drugs and solubilization of cosmetics. Kolliphor EL is suitable for the production of semi-solid and liquid formulations of water-insoluble actives and other hydrophobic compounds. Due to its emulsification functionality, it finds application in biological membrane- based drug transport studies.

Properties of Cremophor EL

Boiling point:	232.6℃[at 101 325 Pa]
Density	1.05 g/mL at 20 °C
vapor pressure	0Pa at 25℃
Flash point:	257℃
storage temp.	REFRIGERATOR (+4C)
solubility	Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
pka	0[at 20 ℃]
form	Viscous Liquid
color	Clear yellow
PH	5.0-7.0 (1g/10 mL in H2O)
Odor	at 100.00?%. bland
Water Solubility	24.11mg/L at 25℃
Stability:	Stable. Incompatible with storng oxidizing agents.
CAS DataBase Reference	61791-12-6
EPA Substance Registry System	Ethoxylated castor oil (61791-12-6)