COENZYME Q9

Chemical properties

Bright Yellow Solid

The Uses of COENZYME Q9

Antibacterial and antioxidant for preventing and treating cancer.

The Uses of COENZYME Q9

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia. Ubidecarenone impurity D may be used as an internal standard for the determination of the ubiquinol-10 in biological samples by high performance chromatography method(HPLC) and liquid chromatography tandem mass spectrometry to evaluate the oxidative stress.

The Uses of COENZYME Q9

Coenzyme Q₉ has been used to investigate its interference in the detection of coenzyme Q₁₀ (CoQ₁₀) by fluorescent spectrophotometer (FS-ECA). It has also been used as an analyte in chromatographic analysis of different biological samples that correspond to different genetic conditions.

What are the applications of Application

Coenzyme Q9 is a useful tool in vitro to increase the life span of cells

Definition

ChEBI: Ubiquinone-9 is a member of ubiquinones. It has a role as an antioxidant and a human metabolite.

General Description

Coenzyme Q9 (Ubiquinone-9; Ubi-9) is a 9 isoprenyl group member of a family of ubiquinones that share a quinine chemical group but differ in the number of isoprenyl chemical subunits in their tail. The CoQ compounds are lipid soluble components of cell membranes.

Biochem/physiol Actions

The coenzyme Q (CoQ) can perform multiple functions such as electron and proton transport. CoQ9 performs similar functions to CoQ10 as the native CoQ in Caenorhabditis elegans. CoQ9 as well as other CoQ molecules may have an impact on cell life-span and these molecules are seeing increase usage in such studies.

Purification Methods

The yellow crystals are purified by recrystallisation from pet ether and by chromatography on SiO2 plates and eluted with Et2O/hexane. The purity can be checked by HPLC (silica column using 7% Et2O/hexane). It has max 270nm ( 14,850) in pet ether. [NMR and MS: Naruta J Org Chem 45 4097 1980, Le et al. Biochem Biophys Acta 32 497 1958, cf Morton Biochemical Spectroscopy (Adam Hilger, London, 1975) p 491, IR: Lester et al. Biochim Biophys Acta 33 169 1959, UV: Rüegg et al. Helv Chim Acta 42 2616 1959, Shunk J Am Chem Soc 81 5000 1959, Beilstein 8 IV 3313.]