citreoviridin
- CAS NO.：25425-12-1
- Empirical Formula: C23H30O6
- Molecular Weight: 402.48
- MDL number: MFCD28015902
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 09:01:59
What is citreoviridin?
Chemical properties
Yellow powder
The Uses of citreoviridin
Citreoviridin is the dominant analogue of a family of tetraene mycotoxins with potent neurotoxic effects, produced by several species of Aspergillus and Penicillium. Citreoviridin inhibits mitochondrial ATPase and is a causative agent of cardiac beriberi.
The Uses of citreoviridin
Citreoviridin is a mycotoxin isolated from several Penicillium species that has been shown to inhibit the mitochondrial ATP synthetase system. It inhibits soluble ATPase (KD = 4.1 μM), ADP-stimulated respiration in isolated rat liver mitochondria (KD = 0.15 μM), and ATP-driven reduction of NAD+ by succinate (KD = 2 μM). Citreoviridin has been used to target ectopic ATPase activity in cancer cells in order to modulate the metabolic activity associated with tumorigenesis.[Cayman Chemical]
What are the applications of Application
Citreoviridin is a mycotoxin and potent inhibitor of mitochondrial ATPase
Definition
ChEBI: Citreoviridin is a member of 2-pyranones.
Properties of citreoviridin
| Melting point: | 107-111℃ |
| Boiling point: | 444.62°C (rough estimate) |
| Density | 1.1271 (rough estimate) |
| refractive index | 1.4593 (estimate) |
| storage temp. | 2-8°C |
| solubility | DMSO: 10 mg/ml; Ethanol: 10 mg/ml |
| pka | 13.67±0.70(Predicted) |
| form | Yellow to orange powder. |
| Stability: | Light Sensitive |
Safety information for citreoviridin
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H300:Acute toxicity,oral H311:Acute toxicity,dermal H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H331:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H361:Reproductive toxicity |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P311:Call a POISON CENTER or doctor/physician. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for citreoviridin
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