CIS-ENTACAPONE
Synonym(s):(Z)-Entacapone;(2Z)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide
- CAS NO.：145195-63-7
- Empirical Formula: C14H15N3O5
- Molecular Weight: 305.29
- MDL number: MFCD00869878
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-08-20 16:56:23
What is CIS-ENTACAPONE?
Description
cis-Entacapone is a metabolite of the catechol-O-methyltransferase (COMT) inhibitor entacapone . It is also a potential impurity found in commercial preparations of entacapone and a degradant of entacapone formed by UV light exposure.
Chemical properties
Orange Solid
The Uses of CIS-ENTACAPONE
cis-Entacapone (Entacapone EP Impurity A) is the (Z)-Isomer of Entacapone polymorphic form B. Antiparkinsonian.
What are the applications of Application
cis-Entacapone is a (Z)-Isomer of Entacapone polymorphic form B
Definition
ChEBI: 2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide is a hydroxycinnamic acid.
Properties of CIS-ENTACAPONE
| Melting point: | 142-144°C |
| Boiling point: | 526.6±50.0 °C(Predicted) |
| Density | 1.392±0.06 g/cm3(Predicted) |
| storage temp. | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
| solubility | Dichloromethane (Slightly), Methanol (Slightly) |
| form | neat |
| pka | 5.15±0.50(Predicted) |
| color | Yellow to Orange |
Safety information for CIS-ENTACAPONE
Computed Descriptors for CIS-ENTACAPONE
New Products
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