cis-4-Hydroxy-D-proline hydrochloride
- CAS NO.:77449-94-6
- Empirical Formula: C5H10ClNO3
- Molecular Weight: 167.5908
- MDL number: MFCD09749867
- EINECS: 1592732-453-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:55:01
What is cis-4-Hydroxy-D-proline hydrochloride?
The Uses of cis-4-Hydroxy-D-proline hydrochloride
Cis-4-Hydroxy-D-proline, HCl
Synthesis
A mixture of (2S,4R)-4-hydroxypyrrolidine-2-carboxylicacid(50 mmol, 6550 mg) and Ac2O (250 mmol, 23.5 mL) in AcOH (100 mL) wasstirred at reflux for 6 h. The resulting mixture was concentrated to give thecrude intermediate. The solution of this crude intermediate in 2 N HCl (50 mL)was stirred at reflux for 3 h. Then activated charcoal (1 g) was added, the hotmixture was ltered immediately through a Celite layer. The filtrate was concentrated in vacuo to give the crude intermediate.The crude intermediate was dissolved in acetone and filtered. The residue was washed twice with ether anddried in vacuo to give cis-4-Hydroxy-D-proline hydrochloride as a white solid (7.54 g, 90percent).
Properties of cis-4-Hydroxy-D-proline hydrochloride
Melting point: | 114-116 °C |
storage temp. | Inert atmosphere,Room Temperature |
form | Solid |
color | White to off-white |
InChI | InChI=1/C5H9NO3.ClH/c7-3-1-4(5(8)9)6-2-3;/h3-4,6-7H,1-2H2,(H,8,9);1H/t3-,4-;/s3 |
Safety information for cis-4-Hydroxy-D-proline hydrochloride
Computed Descriptors for cis-4-Hydroxy-D-proline hydrochloride
InChIKey | YEJFFQAGTXBSTI-QYDODFSFNA-N |
SMILES | C(O)(=O)[C@H]1C[C@@H](O)CN1.[H]Cl |&1:3,5,r| |
Abamectin manufacturer
Tulasi Labs
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Whatsapp: +91-8106722317
product: 77449-94-6 (2R,4R)-4-hydroxypyrrolidine-2-carboxylic acid hydrochloride 98%
ARRKEM LIFE SCIENCES PRIVATE LIMITED
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Phone:+91-8148739767
Whatsapp: +91-8148739767
product: 77449-94-6 98%
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