CI 1020
Synonym(s):α-[2-(4-Methoxyphenyl)-2-oxo-1-[(3,4,5-trimethoxyphenyl)methyl]ethylidene]-1,3-benzodioxole-5-acetic acid sodium salt
- CAS NO.：162256-50-0
- Empirical Formula: C28H26O9
- Molecular Weight: 506.5
- MDL number: MFCD00867525
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-18 11:31:04
What is CI 1020?
The Uses of CI 1020
A novel endothelin-A receptor antagonist, in hypoxic pulmonary hypertension.
What are the applications of Application
CI 1020 is a highly selective non-peptide ETAR antagonist
Biological Activity
Highly selective, orally active, non-peptide endothelin-A receptor (ET A ) antagonist (IC 50 values are 0.3 and 480 nM for ET A and ET B receptors respectively). Antihypertensive; blocks ET-1-induced pressor responses following oral administration.
Properties of CI 1020
| storage temp. | Store at +4°C |
| solubility | Soluble to 50 mM in DMSO |
| form | Powder |
Safety information for CI 1020
Computed Descriptors for CI 1020
New Products
Tubulysin B Tubulysin G (R)-tert-butyl (4-methyl-1-oxopentan-3-yl)carbamate Tubulysin C Tubulysin M Potassium HMDS (1.0 M in THF) 3-N-BOC-(S)-AMINO BUTYRONITRILE 2-(azetidin-3-ylidene)acetonitrile (hydrochloride) 3-METHYLAZETIDIN-3-OL HYDROCHLORIDE 2,2-Difluoropropanol 2,2-Difluoropropylamine hydrochloride 4-(Benzyloxy)-3-bromophenylacetic Acid Fuel shell Calcium Sodium Phosphosilicate IH (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Imeglimin Hydrochloride IH 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol Latanoprostene Bunod Magnesium Trisilicate Lubiprostone Flame Retardant Zinc Borate methyl 3-fluoro-4- thiomorpholino phenylcarbamate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonateRelated products of tetrahydrofuran
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