CI 1020

Synonym(s):α-[2-(4-Methoxyphenyl)-2-oxo-1-[(3,4,5-trimethoxyphenyl)methyl]ethylidene]-1,3-benzodioxole-5-acetic acid sodium salt

CAS NO.：162256-50-0
Empirical Formula: C28H26O9
Molecular Weight: 506.5
MDL number: MFCD00867525
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-23 13:36:13

What is CI 1020?

The Uses of CI 1020

A novel endothelin-A receptor antagonist, in hypoxic pulmonary hypertension.

What are the applications of Application

CI 1020 is a highly selective non-peptide ETAR antagonist

Biological Activity

Highly selective, orally active, non-peptide endothelin-A receptor (ET A ) antagonist (IC 50 values are 0.3 and 480 nM for ET A and ET B receptors respectively). Antihypertensive; blocks ET-1-induced pressor responses following oral administration.

Properties of CI 1020

storage temp.	Store at +4°C
solubility	Soluble to 50 mM in DMSO
form	Powder

Safety information for CI 1020

Computed Descriptors for CI 1020

New Products

ALUMINIUM IODIDE 100 GM BUFFER CAPSULE PH 7.0 - 10 CAP BUFFER SOLUTION PH 9.5 (BORATE) EZEE BLUE GEL STAINER BORAX CARMINE (GRENACHERS ALCOHOLIC) POTASSIUM IODATE - IODIDE SOLN 0.1 N Dabigatran Acyl-O3-D-Glucuronide Trifluoroacetic Acid Salt Isofolic Acid Dabigatran 2-O-acylglucuronide metabolite Dabigatran Acyl-?-D- glucuronide Trifluroacetic Acid Erythromycin EP Impurity A Desloratidine Related Compound A

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