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HomeProduct name listCI 1020

CI 1020

Synonym(s):α-[2-(4-Methoxyphenyl)-2-oxo-1-[(3,4,5-trimethoxyphenyl)methyl]ethylidene]-1,3-benzodioxole-5-acetic acid sodium salt

CI 1020 Structural

What is CI 1020?

The Uses of CI 1020

A novel endothelin-A receptor antagonist, in hypoxic pulmonary hypertension.

What are the applications of Application

CI 1020 is a highly selective non-peptide ETAR antagonist

Biological Activity

Highly selective, orally active, non-peptide endothelin-A receptor (ET A ) antagonist (IC 50 values are 0.3 and 480 nM for ET A and ET B receptors respectively). Antihypertensive; blocks ET-1-induced pressor responses following oral administration.

Properties of CI 1020

storage temp.  Store at +4°C
solubility  Soluble to 50 mM in DMSO
form  Powder

Safety information for CI 1020

Computed Descriptors for CI 1020

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