CECROPIN A
- CAS NO.：80451-04-3
- Empirical Formula: C184H313N53O46
- Molecular Weight: 4003.78152
- MDL number: MFCD00130752
- Update Date: 2024-11-19 23:02:33
What is CECROPIN A?
The Uses of CECROPIN A
Cecropin A is an antibacterial peptide originally identified in moths.
The Uses of CECROPIN A
Cecropin A has been used as an antimicrobial peptide (AMP):
- to test its cytotoxic effect on breast adenocarcinoma (MDA-MB-231) and human mesothelioma (M14K) cell lines
- in ultrasensitive radial diffusion assay against E coli to test Galleria mellonella protein 24 and apolipophorin III effects
- to test its minimal inhibitory concentrations (MICs) in sensitivity assay for Photorhabdus variants
What are the applications of Application
Cecropin A is an antibacterial peptide originally identified in moths
General Description
Cecropin A belongs to cecropin class and comprises 37 amino acid residues in L configuration. Structurally, this peptide has a C-terminal hydrophobic α-helical structure and the amphipathic N-terminal end. Cecropin A is linear and cationic in nature.
Biochem/physiol Actions
Cecropin A interacts with cell membranes and makes it permeable for electrolytes. Cecropin A thus, favors cytolysis and finally cell death in the hepatocellular carcinoma and lymphoma. The synthetic cecropin A in transgenic rice confers protection against bacterial as well as fungal pathogens.
Properties of CECROPIN A
| storage temp. | -20°C |
| form | powder |
| color | White to off-white |
| Water Solubility | Water : ≥ 50 mg/mL (12.14 mM) |
Safety information for CECROPIN A
Computed Descriptors for CECROPIN A
New Products
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