CAPECITABINE-D11
- CAS NO.:1132662-08-8
- Empirical Formula: C15H13D11FN3O6
- Molecular Weight: 372.43
- MDL number: MFCD10567126
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 09:03:08
What is CAPECITABINE-D11?
Description
Capecitabine-d11 is intended for use as an internal standard for the quantification of capecitabine by GC- or LC-MS. Capecitabine is a prodrug form of 5-fluorouracil (5-FU). It is converted to 5-FU via several enzymatic steps beginning in the liver and ending with conversion in tumor tissue by thymidine phosphorylase, an enzyme that is more concentrated in tumor tissue compared with normal tissue. Capecitabine is cytotoxic only at high concentrations in Scaber, SIHA, and MKN45 cells (IC50s = 97, 578, and 994 μM, respectively) and is inactive in a variety of cancer cell lines, including COLO 205, HCT116, and MCF-7 cells (IC50s = >1,000 μM).
Chemical properties
Off-White Powder
The Uses of CAPECITABINE-D11
An isotopically labelled antineoplastic agent. A prodrug of Doxifluridine (D556750).
The Uses of CAPECITABINE-D11
Capecitabine D11 is an isotopically labelled antineoplastic agent. A prodrug of Doxifluridine.;Labeled Capecitabine, intended for use as an internal standard for the quantification of Capecitabine by GC- or LC-mass spectrometry.
What are the applications of Application
Capecitabine-d11 is an isotopically labelled antineoplastic agent
Properties of CAPECITABINE-D11
Melting point: | 45-50°C |
storage temp. | -20°C Freezer, Under Inert Atmosphere |
solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
form | Solid |
color | Off-White to Pale Yellow Waxy |
Safety information for CAPECITABINE-D11
Computed Descriptors for CAPECITABINE-D11
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