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HomeProduct name listCALMODULIN

CALMODULIN

Synonym(s):CaM;CaM, Ca 2+/Calmodulin;CaM, Ca2+/Calmodulin;Phosphodiesterase 3′:5′-cyclic nucleotide activator;Phosphodiesterase 3′:5′-cyclic nucleotide activator from bovine heart

What is CALMODULIN?

The Uses of CALMODULIN

Activates cyclic phosphodiesterase

The Uses of CALMODULIN

This is the protein activator required for the Ca2+ dependent activation of phosphodiesterase, 3′:5′-cyclic nucleotide, P0520.

Definition

A protein, consistingof 148 amino-acid residues, that actsas a receptor for calcium ions inmany calcium-regulated processes inboth animal and plant cells. Calmodulinmediates reactions catalysed bymany enzymes.

Biochem/physiol Actions

Ca2+ binding protein that is required for activation of cyclic nucleotide-dependent phosphodiesterase. It is also a cofactor/activator of nitric oxide synthase, calcineurin, and many kinases including ATPase, myosin light chain kinase, and CAM kinase I, II, and III. It mediates ryanodine receptor activation by cyclic ADP ribose and is involved in intracellular Ca2+ homeostasis.

Properties of CALMODULIN

storage temp.  -20°C
form  lyophilized powder
Water Solubility  Soluble in water at 1mg/ml

Safety information for CALMODULIN

Computed Descriptors for CALMODULIN

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