Butyl salicylate

CAS NO.：2052-14-4
Empirical Formula: C11H14O3
Molecular Weight: 194.23
MDL number: MFCD00020038
EINECS: 218-142-9
SAFETY DATA SHEET (SDS)
Update Date: 2024-06-11 14:09:09

What is Butyl salicylate?

Chemical properties

Butyl salicylate has a rough, herbaceous, chemical odor with a trace of wintergreen.

Occurrence

Reported found in mountain papaya.

The Uses of Butyl salicylate

Butyl salicylate is used in perfume compositions as a modifier for higher esters of Salicylic acid. It produces a Fougere-like note with Coumarin and Lavandin - with or without Oakmoss - but not as attractive as the one obtainable with the Amylester. Blends well with the herbaceous oils, with Pine needle oils and related chemicals (Bornyl family), with Cedarwood producls and it gives good fixative effect along with the simple Nitromusks in low-cost perfumes.

Preparation

By direct esterification of n-butanol with salicylic acid under azeotropic conditions.

Definition

ChEBI: Butyl salicylate is a member of phenols and a benzoate ester. It is functionally related to a salicylic acid.

Aroma threshold values

Detection 5 to 7 ppb; Recognition 10 ppb

Synthesis Reference(s)

Tetrahedron Letters, 37, p. 6375, 1996 DOI: 10.1016/0040-4039(96)01351-2

Properties of Butyl salicylate

Melting point:	-5.9°C
Boiling point:	268 °C (lit.)
Density	1.08 g/mL at 25 °C (lit.)
refractive index	1.5120
FEMA	3650 \| BUTYL SALICYLATE
Flash point:	134°C
form	liquid
pka	8.15±0.30(Predicted)
color	Colorless to Almost colorless
Odor	Somewhat rough-herbaceous-chemical odor
Water Solubility	2.8g/L(37 ºC)
JECFA Number	901
CAS DataBase Reference	2052-14-4(CAS DataBase Reference)
NIST Chemistry Reference	Benzoic acid, 2-hydroxy-, butyl ester(2052-14-4)
EPA Substance Registry System	Benzoic acid, 2-hydroxy-, butyl ester (2052-14-4)

Safety information for Butyl salicylate

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P501:Dispose of contents/container to..…