Brassinolide

Description

Brassinolide is a natural steroid that promotes cell elongation and division in plants. In 1979, M. D. Grove and colleagues isolated it from?Brassica napus(rapeseed) pollen and characterized it. This year, research groups in the United States and China, working separately, showed that?a plant hormone receptor protein that senses brassinolide has a superhelix conformation.

Chemical properties

Off-White Solid

The Uses of Brassinolide

Brassinolide can be used as plant growth regulator.

The Uses of Brassinolide

Plant growth regulator.

The Uses of Brassinolide

Brassinolide has been used as a plant growth hormone.

What are the applications of Application

Brassinolide is a plant growth hormone that has been implicated in Auxin signaling

Definition

ChEBI: Brassinolide is a 2alpha-hydroxy steroid, a 3alpha-hydroxy steroid, a 22-hydroxy steroid, a 23-hydroxy steroid and a brassinosteroid. It has a role as a plant growth stimulator and a plant hormone.

General Description

Brassinolide is a plant growth hormone and the most biologically active brassinosteroid (BR). It has been implicated in Auxin signaling. It has also been used for studying plant biosynthetic pathways. Brassinolide might also regulate water-transport properties of cell membranes in Arabidopsis thaliana.

Biological Activity

brassinolide is a plant growth regulator. plant growth regulators are naturally produced by plants and are critical for regulating their own growth. plant growth regulators act via modifying or controlling plant growth processes, such as leave and flower formation, stem elongation, as well as fruit development and ripening.

Biochem/physiol Actions

Brassinolide is a plant growth hormone that has been implicated in Auxin signaling. It has also been used for studying plant biosynthetic pathways.

in vitro

brassinolide induced the time and concentration-dependent cytotoxicity in pc-3 cells. the mode of such cell death appeared to be apoptosis predominately, as demonstrated by fluorescence, flow-cytometric analyses and transmission electron microscopes. moreover, caspase-3 activity was increased after brassinolide treatment obviously. western blot studies showed brassinolide treatment triggered a time-dependent decrease in the expression of bcl-2 [1].

in vivo

brassinolide had the similar function of reducing the blood glucose levels as phenformin, but without the dose-dependent manner. the blood glucose levels showed significant differences after brassinolide treatment with different doses (200, 100, and 50 mg/kg). these results indicated that brassinolide could reduce the blood glucose levels without toxicity [2].

References

[1] wu yd,lou yj. brassinolide, a plant sterol from pollen of brassica napus l., induces apoptosis in human prostate cancer pc-3 cells. pharmazie.2007 may;62(5):392-5.
[2] chen shi-ping, he jia, wang qi-jing, wang jian-dong, ye yan-li, xian li-jian. effect of brassinolide on levels of blood glucose in alloxan—induced diabetes rats. acta metallurgica sinica, 2009,v26(03): 21-23