Br-PEG7-OH
- CAS NO.：86220-35-1
- Empirical Formula: C14H29BrO7
- Molecular Weight: 389.28
- MDL number: MFCD31656971
- Update Date: 2024-10-23 13:36:13
What is Br-PEG7-OH?
Biological Activity
Bromo-PEG7-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Properties of Br-PEG7-OH
| Boiling point: | 443.0±40.0 °C(Predicted) |
| Density | 1.261±0.06 g/cm3(Predicted) |
| form | Liquid |
| pka | 14.36±0.10(Predicted) |
| color | Colorless to light yellow |
Safety information for Br-PEG7-OH
Computed Descriptors for Br-PEG7-OH
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