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HomeProduct name listBOLTON-HUNTER REAGENT

BOLTON-HUNTER REAGENT

Synonym(s):N-[(4-Hydroxyhydrocinnamoyl)oxy]succinimide;N-Succinimidyl 3-(4-hydroxyphenyl)propionate;Bolton-Hunter reagent precursor;Rudinger reagent;SHPP

  • CAS NO.:34071-95-9
  • Empirical Formula: C13H13NO5
  • Molecular Weight: 263.25
  • MDL number: MFCD00005515
  • EINECS: 251-818-1
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-08-02 20:38:39
BOLTON-HUNTER REAGENT Structural

What is BOLTON-HUNTER REAGENT?

Chemical properties

white to off-white powder

The Uses of BOLTON-HUNTER REAGENT

Bolton-Hunter Reagent is used for iodination of proteins that do not contain tyrosine residues, Bolton-Hunter reagent precursor (3-(4-Hydroxyphenyl)propionic acid N-hydroxysuccinimide ester) is a hydroxysuccinimide ester used as an intermediate for high radioactive radioiodination of proteins.

The Uses of BOLTON-HUNTER REAGENT

3-(4-Hydroxyphenyl)propionic acid?N-hydroxysuccinimide ester can be used to prepare 125I-labeled reagents, which are used in binding assay studies of proteins and peptides.

What are the applications of Application

3-(4-Hydroxyphenyl)propionic acid N-hydroxysuccinimide ester is an intermediate for high 128I-labeling of proteins

Properties of BOLTON-HUNTER REAGENT

Melting point: 132-133 °C(lit.)
Boiling point: 406.49°C (rough estimate)
Density  1.2705 (rough estimate)
refractive index  1.5480 (estimate)
storage temp.  -20°C
solubility  Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (
form  Solid
pka 9.93±0.15(Predicted)
color  White to Light Orange
Water Solubility  Soluble in water.
BRN  1545011

Safety information for BOLTON-HUNTER REAGENT

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405:Store locked up.

Computed Descriptors for BOLTON-HUNTER REAGENT

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