Boldenone
- CAS NO.:846-48-0
- Empirical Formula: C19H26O2
- Molecular Weight: 286.41
- MDL number: MFCD00037712
- EINECS: 212-686-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-09-23 17:56:10
What is Boldenone?
Description
Boldenone (Item No. 15432) is an analytical reference standard categorized as an anabolic androgenic steroid. Anabolic steroids, including boldenone, have been used to enhance physical performance in athletes. Boldenone is regulated as a Schedule III compound in the United States. This product is intended for research and forensic applications.
Chemical properties
Crystalline Solid
The Uses of Boldenone
Controlled substance. Anabolic steroid
The Uses of Boldenone
Boldenone is an anabolic steroid. Controlled substance.
Definition
ChEBI: An 3-oxo-Delta1,Delta4-steroid substituted by an oxo group at position 3 and a beta-hydroxy group at position 17. It is an anabolic androgenic steroid that has been eveloped for veterinary use.
brand name
Equipoise [Veterinary] (Fort Dodge Animal Health).
Synthesis
Boldenone is obtained by reacting Testosterone with tert-butyldimethylsilyl chloride in the presence of DDQ.
Experimental Procedure: 29.0 g Testosterone was dissolved in 220 ml dioxan/THF 8:2 and cooled to 0°C on ice. After
cooling down a solution of tert-butyldimethylsilyl chloride (46.0 g in 100 ml dioxan/THF 8:2)
was added dropwise and stirred for 90 min at 0°C. Then a suspension of 32.0 g of DDQ in 200
ml dioxan/THF 8:2 was added in 4 equal portions over a period of 4 h. The reaction mixture
was stirred for additional 12 h within coming from 0°C to room temperature.
The resulting suspension was then filtered over Celite and rinsed with 300 ml THF. The filtrate
was evaporated and brown oil was obtained. The oil was diluted in 1500 ml DCM and washed
with 500 ml of 5% aqueous sodium hydroxide. The yellow organic phase was washed with 400
ml water and 400 ml saturated sodium chloride solution, before drying over magnesium sulfate.
After evaporation, the crude product was chromatographed on silica gel by using hexane-ethyl
acetate (3:7), followed by a recrystallization in ethyl acetate. 16.50 g of Boldenone was obtained as
an amber solid (58%).
Properties of Boldenone
Melting point: | 164-166°C |
alpha | D25 +25° (in chloroform) |
Boiling point: | 368.77°C (rough estimate) |
Density | 1.0655 (rough estimate) |
refractive index | 1.4709 (estimate) |
storage temp. | Controlled Substance, -20°C Freezer |
solubility | DMF: 25 mg/ml; DMSO: 15 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 10 mg/ml |
form | A crystalline solid |
pka | 15.05±0.60(Predicted) |
Water Solubility | 57.1mg/L at 20℃ |
InChI | InChI=1/C19H26O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h7,9,11,14-17,21H,3-6,8,10H2,1-2H3/t14-,15-,16-,17-,18-,19-/s3 |
CAS DataBase Reference | 846-48-0(CAS DataBase Reference) |
NIST Chemistry Reference | Boldenone(846-48-0) |
Safety information for Boldenone
Computed Descriptors for Boldenone
InChIKey | RSIHSRDYCUFFLA-KRHBYBJCNA-N |
SMILES | [C@@]12([H])CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@H](CC[C@@]21[H])O |&1:0,10,12,16,18,21,r| |
Abamectin manufacturer
Orgamine Chemicals(I) Pvt Ltd
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