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HomeProduct name listBoldenone

Boldenone

  • CAS NO.:846-48-0
  • Empirical Formula: C19H26O2
  • Molecular Weight: 286.41
  • MDL number: MFCD00037712
  • EINECS: 212-686-0
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-09-23 17:56:10
Boldenone Structural

What is Boldenone?

Description

Boldenone (Item No. 15432) is an analytical reference standard categorized as an anabolic androgenic steroid. Anabolic steroids, including boldenone, have been used to enhance physical performance in athletes. Boldenone is regulated as a Schedule III compound in the United States. This product is intended for research and forensic applications.

Chemical properties

Crystalline Solid

The Uses of Boldenone

Boldenone is an anabolic steroid. Controlled substance.

The Uses of Boldenone

Controlled substance. Anabolic steroid

Definition

ChEBI: An 3-oxo-Delta1,Delta4-steroid substituted by an oxo group at position 3 and a beta-hydroxy group at position 17. It is an anabolic androgenic steroid that has been eveloped for veterinary use.

brand name

Equipoise [Veterinary] (Fort Dodge Animal Health).

Synthesis

Boldenone is obtained by reacting Testosterone with tert-butyldimethylsilyl chloride in the presence of DDQ.
Experimental Procedure: 29.0 g Testosterone was dissolved in 220 ml dioxan/THF 8:2 and cooled to 0°C on ice. After cooling down a solution of tert-butyldimethylsilyl chloride (46.0 g in 100 ml dioxan/THF 8:2) was added dropwise and stirred for 90 min at 0°C. Then a suspension of 32.0 g of DDQ in 200 ml dioxan/THF 8:2 was added in 4 equal portions over a period of 4 h. The reaction mixture was stirred for additional 12 h within coming from 0°C to room temperature. The resulting suspension was then filtered over Celite and rinsed with 300 ml THF. The filtrate was evaporated and brown oil was obtained. The oil was diluted in 1500 ml DCM and washed with 500 ml of 5% aqueous sodium hydroxide. The yellow organic phase was washed with 400 ml water and 400 ml saturated sodium chloride solution, before drying over magnesium sulfate. After evaporation, the crude product was chromatographed on silica gel by using hexane-ethyl acetate (3:7), followed by a recrystallization in ethyl acetate. 16.50 g of Boldenone was obtained as an amber solid (58%).

Properties of Boldenone

Melting point: 164-166°C
alpha  D25 +25° (in chloroform)
Boiling point: 368.77°C (rough estimate)
Density  1.0655 (rough estimate)
refractive index  1.4709 (estimate)
storage temp.  Controlled Substance, -20°C Freezer
solubility  DMF: 25 mg/ml; DMSO: 15 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 10 mg/ml
form  A crystalline solid
pka 15.05±0.60(Predicted)
Water Solubility  57.1mg/L at 20℃
InChI InChI=1/C19H26O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h7,9,11,14-17,21H,3-6,8,10H2,1-2H3/t14-,15-,16-,17-,18-,19-/s3
CAS DataBase Reference 846-48-0(CAS DataBase Reference)
NIST Chemistry Reference Boldenone(846-48-0)

Safety information for Boldenone

Computed Descriptors for Boldenone

InChIKey RSIHSRDYCUFFLA-KRHBYBJCNA-N
SMILES [C@@]12([H])CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@H](CC[C@@]21[H])O |&1:0,10,12,16,18,21,r|

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