BOC-D-3,4-Dichlorophe

Synonym(s):Boc-3,4-dichloro-D-phenylalanine

CAS NO.：114873-13-1
Empirical Formula: C14H17Cl2NO4
Molecular Weight: 334.2
MDL number: MFCD00151887
SAFETY DATA SHEET (SDS)
Update Date: 2024-07-02 08:55:14

What is BOC-D-3,4-Dichlorophe?

Chemical properties

white to off-white powder

The Uses of BOC-D-3,4-Dichlorophe

N-Boc-D-3,4-dichlorophenylalanine is used to prepare fluorinated β-aminoacyl 1,2,4-triazolo[4,3-a]piperazine amides as dipeptidyl peptidase IV inhibitors and antidiabetic agents. It is also used in the synthesis of N-[(R,R)-(E)-1-(3,4-dichlorobenzyl)-3- (2-oxoazepan-3-yl)carbamoyl]allyl-N-methyl-3,5-bis(trifluoromethyl)benzamide as a potent and orally active dual neurokinin NK1/NK2 receptor antagonist.

Properties of BOC-D-3,4-Dichlorophe

Melting point:	120°C
Boiling point:	478.1±45.0 °C(Predicted)
alpha	-15 º (c=1,MeOH)
Density	1.3859 (rough estimate)
refractive index	1.6200 (estimate)
storage temp.	Sealed in dry,Room Temperature
form	Solid
pka	3.75±0.10(Predicted)
color	White to off-white
BRN	8428163
CAS DataBase Reference	114873-13-1(CAS DataBase Reference)

Safety information for BOC-D-3,4-Dichlorophe

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.