BISINDOLYLMALEIMIDE III
- CAS NO.：137592-43-9
- Empirical Formula: C23H20N4O2
- Molecular Weight: 384.43
- MDL number: MFCD01076633
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-16 15:32:52
What is BISINDOLYLMALEIMIDE III?
Description
Bisindolylmaleimide III was developed as a protein kinase C (PKC) inhibitor with structural similarity to the nonspecific PKC inhibitor staurosporine. At 1 μM, bisindolylmaleimide III inhibits 93% of PKCα kinase activity and also inhibits many other protein kinases including, S6K1, MAPKAP-
The Uses of BISINDOLYLMALEIMIDE III
Bisindolylmaleimide III is a protein kinase C inhibitor and was also shown to exhibit inhibitory activities towards PDK1, an important kinase in the insulin signaling pathway,
What are the applications of Application
Bisindolylmaleimide III is a potent and selective inhibitor of PKC
Definition
ChEBI: Bisindolylmaleimide III is a member of maleimides and a member of indoles. It has a role as an EC 2.7.11.13 (protein kinase C) inhibitor. It is functionally related to a maleimide.
Properties of BISINDOLYLMALEIMIDE III
| Boiling point: | 708.7±60.0 °C(Predicted) |
| Density | 1.41±0.1 g/cm3(Predicted) |
| solubility | DMSO: soluble; Methanol: soluble |
| form | A crystalline solid |
| pka | 8.15±0.60(Predicted) |
| color | Brown to reddish brown |
Safety information for BISINDOLYLMALEIMIDE III
Computed Descriptors for BISINDOLYLMALEIMIDE III
New Products
4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION Methylcobalamin (vitamin B12) SODIUM METHYL PARABEN SODIUM VALPROATE AMOXICILLIN (AMOXYCILLIN) TRIHYDRATE ACICLOVIRRelated products of tetrahydrofuran
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