Biotin-PEG3-CH2COOH
- CAS NO.：1189560-96-0
- Empirical Formula: C18H31N3O7S
- Molecular Weight: 433.52
- MDL number: MFCD30749255
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-02-23 14:24:00
What is Biotin-PEG3-CH2COOH?
Biological Activity
Biotin-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Safety information for Biotin-PEG3-CH2COOH
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