Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name listBETA-ENDORPHIN HUMAN SYNTHETIC

BETA-ENDORPHIN HUMAN SYNTHETIC

Synonym(s):β-Lipotropin 61-91;β-Lipotropin C-fragment;LPH (61-91)

  • CAS NO.:61214-51-5
  • Empirical Formula: C158H251N39O46S
  • Molecular Weight: 3464.99
  • MDL number: MFCD00076383
  • EINECS: 262-330-3
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-08-28 13:53:23
BETA-ENDORPHIN  HUMAN  SYNTHETIC Structural

What is BETA-ENDORPHIN HUMAN SYNTHETIC?

The Uses of BETA-ENDORPHIN HUMAN SYNTHETIC

beta-endorphins produce analgesia by binding to opioid receptors (particularly of the mu subtype) at both pre- and post- synaptic nerve terminals, primarily exerting their effect through presynaptic binding. In the central nervous system, beta-endorphins similarly bind mu-opioid receptors and exert their primary action at presynaptic nerve terminals. It is a potent pain suppressant.

General Description

β-Endorphin is a potent endogenous opioid protein that is derived from propiomelanocortin, a protein found in the brain, anterior pituitary, skin, immune system, and other peripheral sites. β-endorphin, however, is localized to the brain and spinal cord. It is one of the major opioid peptides, and is the derivative of the C-terminal of β-lipotropin. It is made of 31 amino acids.

Biochem/physiol Actions

β-Endorphin acts as a ligand for both μ and δ opioid receptors in different parts of the brain. It is released in response to painful stimuli and has potent antinociceptive activity. When given supraspinally, this activity is mediated through its action on ε-opioid receptors in brain that results in the release of Met-enkephalin. This activity is also mediated by its interaction with δ2-opioid receptors in the spinal cord. When introduced intrathecally, this function is an outcome of its interaction with μ and κ-opioid receptors in the rat. In autoimmune disorders, the elevated production of cytokines results in the production of β-endorphin, in pituitary and lymphocytes. This acts as a negative regulator of antibody production, and is thus, implicated in autoimmune diseases.

Properties of BETA-ENDORPHIN HUMAN SYNTHETIC

Boiling point: 2931.7±65.0 °C(Predicted)
Density  1.302±0.06 g/cm3(Predicted)
storage temp.  −20°C
solubility  Soluble in DMSO
form  Powder
color  White to off-white
Water Solubility  Soluble in water.

Safety information for BETA-ENDORPHIN HUMAN SYNTHETIC

Computed Descriptors for BETA-ENDORPHIN HUMAN SYNTHETIC

Related products of tetrahydrofuran

You may like

  • β-Endorphin human CAS 61214-51-5
    β-Endorphin human CAS 61214-51-5
    61214-51-5
    View Details
  • 1-Methyl-6-oxo-1,6-dihydropyridazine-3-carbonitrile 98%
    1-Methyl-6-oxo-1,6-dihydropyridazine-3-carbonitrile 98%
    99903-60-3
    View Details
  • 1823368-42-8 98%
    1823368-42-8 98%
    1823368-42-8
    View Details
  • 2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%
    2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%
    1307449-08-6
    View Details
  • Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 25408-95-1 98%
    Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 25408-95-1 98%
    25408-95-1
    View Details
  • 2-Chloro-5-fluoro-1-methoxy-3-methylbenzene 98%
    2-Chloro-5-fluoro-1-methoxy-3-methylbenzene 98%
    1805639-70-6
    View Details
  • 1784294-80-9 98%
    1784294-80-9 98%
    1784294-80-9
    View Details
  • Lithium Clavulanate
    Lithium Clavulanate
    61177-44-4
    View Details
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.