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HomeProduct name listBENAZEPRILAT

BENAZEPRILAT

BENAZEPRILAT Structural

What is BENAZEPRILAT?

Chemical properties

Crystalline Solid

The Uses of BENAZEPRILAT

Benazeprilat is a metabolite of Benazepril, which is used as an antihypertensive.

What are the applications of Application

Benazeprilat is a potent ACE inhibitor

Definition

ChEBI: A benzazepine that is 1,3,4,5-tetrahydro-2H-1-benzazepin-2-one in which the hydrogen attached to the nitrogen is replaced by a carboxy methyl group and in which the 3-pro-S hydrogen is replaced by the amino roup of (2S)-2-amino-4-phenylbutanoic acid. An angiotensin-converting enzyme inhibitor, it is used as its monoester prodrug benazepril in the treatment of hypertension and heart failure.

Properties of BENAZEPRILAT

Melting point: 270-272°C
alpha  D -200.5° (c = 1 in 3% aqueous NH4OH)
Boiling point: 711.3±60.0 °C(Predicted)
Density  1.34±0.1 g/cm3(Predicted)
storage temp.  -20°C Freezer, Under Inert Atmosphere
solubility  Aqueous Base (Slightly), DMSO (Slightly)
form  Solid
pka 2.17±0.10(Predicted)
color  White to Off-White
CAS DataBase Reference 86541-78-8

Safety information for BENAZEPRILAT

Computed Descriptors for BENAZEPRILAT

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