Azeliragon

CAS NO.：603148-36-3
Empirical Formula: C32H38ClN3O2
Molecular Weight: 532.12
MDL number: MFCD11977600
EINECS: 814-441-9
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-19 23:02:33

What is Azeliragon?

Biological Activity

Azeliragon (TTP488, PF-04494700) is an orally bioavailable small molecule inhibitor that inhibits the receptor for advanced glycation end products (RAGE). RAGE is an immunoglobulin-like cell surface receptor that is overexpressed in the brains of Alzheimer's patients.

Properties of Azeliragon

Boiling point:	667.7±65.0 °C(Predicted)
Density	1.11±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO:50.33(Max Conc. mg/mL);94.58(Max Conc. mM) DMF:5.0(Max Conc. mg/mL);9.4(Max Conc. mM) DMF:PBS (pH 7.2) (1:2):0.33(Max Conc. mg/mL);0.62(Max Conc. mM) Ethanol:50.5(Max Conc. mg/mL);94.9(Max Conc. mM)
form	A crystalline solid
pka	10.16±0.25(Predicted)
color	White to light yellow

Safety information for Azeliragon

Computed Descriptors for Azeliragon

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